The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor
Abstract We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe coronavirus disease 2019 (COVID-19). We combine this new data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are...
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | Journal of NeuroEngineering and Rehabilitation |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12984-022-01089-1 |
| _version_ | 1828339634732531712 |
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| author | Colin K. Franz Nikhil K. Murthy George R. Malik Jean W. Kwak Dom D’Andrea Alexis R. Wolfe Ellen Farr Melanie A. Stearns Swati Deshmukh Jinny O. Tavee Fang Sun Kevin N. Swong Leslie Rydberg R. James Cotton Lisa F. Wolfe James M. Walter John M. Coleman John A. Rogers |
| author_facet | Colin K. Franz Nikhil K. Murthy George R. Malik Jean W. Kwak Dom D’Andrea Alexis R. Wolfe Ellen Farr Melanie A. Stearns Swati Deshmukh Jinny O. Tavee Fang Sun Kevin N. Swong Leslie Rydberg R. James Cotton Lisa F. Wolfe James M. Walter John M. Coleman John A. Rogers |
| author_sort | Colin K. Franz |
| collection | DOAJ |
| description | Abstract We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe coronavirus disease 2019 (COVID-19). We combine this new data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are ulnar (25.1%), common fibular (15.8%), sciatic (13.1%), median (9.8%), brachial plexus (8.7%) and radial (8.2%) nerves at sites known to be vulnerable to mechanical loading. Protection of peripheral nerves should be prioritized in the care of COVID-19 patients. To this end, we report proof of concept data of the feasibility for a wearable, wireless pressure sensor to provide real time monitoring in the intensive care unit setting. |
| first_indexed | 2024-04-13T22:45:32Z |
| format | Article |
| id | doaj.art-665094b344114a9ca0ffdfa9641786c3 |
| institution | Directory Open Access Journal |
| issn | 1743-0003 |
| language | English |
| last_indexed | 2024-04-13T22:45:32Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of NeuroEngineering and Rehabilitation |
| spelling | doaj.art-665094b344114a9ca0ffdfa9641786c32022-12-22T02:26:25ZengBMCJournal of NeuroEngineering and Rehabilitation1743-00032022-10-011911910.1186/s12984-022-01089-1The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensorColin K. Franz0Nikhil K. Murthy1George R. Malik2Jean W. Kwak3Dom D’Andrea4Alexis R. Wolfe5Ellen Farr6Melanie A. Stearns7Swati Deshmukh8Jinny O. Tavee9Fang Sun10Kevin N. Swong11Leslie Rydberg12R. James Cotton13Lisa F. Wolfe14James M. Walter15John M. Coleman16John A. Rogers17Shirley Ryan Ability LabMcGaw Medical Center, Northwestern University Feinberg School of MedicineDepartment of Physiatry, Hospital for Special SurgeryQuerrey Simpson Institute for Bioelectronics, Northwestern UniversityShirley Ryan Ability LabMcGaw Medical Center, Northwestern University Feinberg School of MedicineDepartment of Physical Medicine and Rehabilitation, Mayo Clinic College of Medicine and ScienceMarianjoy Rehabilitation Hospital, Northwestern MedicineDepartment of Radiology, Beth Israel Deaconess Medical CenterDivision of Neurology & Behavioral Health, National Jewish HealthThe Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of MedicineDepartment of Neurological Surgery, Northwestern University Feinberg School of MedicineShirley Ryan Ability LabShirley Ryan Ability LabShirley Ryan Ability LabThe Division of Pulmonary and Critical Care, Department of Medicine, Northwestern University Feinberg School of MedicineThe Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of MedicineQuerrey Simpson Institute for Bioelectronics, Northwestern UniversityAbstract We diagnosed 66 peripheral nerve injuries in 34 patients who survived severe coronavirus disease 2019 (COVID-19). We combine this new data with published case series re-analyzed here (117 nerve injuries; 58 patients) to provide a comprehensive accounting of lesion sites. The most common are ulnar (25.1%), common fibular (15.8%), sciatic (13.1%), median (9.8%), brachial plexus (8.7%) and radial (8.2%) nerves at sites known to be vulnerable to mechanical loading. Protection of peripheral nerves should be prioritized in the care of COVID-19 patients. To this end, we report proof of concept data of the feasibility for a wearable, wireless pressure sensor to provide real time monitoring in the intensive care unit setting.https://doi.org/10.1186/s12984-022-01089-1RehabilitationNeuromuscularCOVID-19Peripheral nerve injuryNeuropathyBrachial plexus |
| spellingShingle | Colin K. Franz Nikhil K. Murthy George R. Malik Jean W. Kwak Dom D’Andrea Alexis R. Wolfe Ellen Farr Melanie A. Stearns Swati Deshmukh Jinny O. Tavee Fang Sun Kevin N. Swong Leslie Rydberg R. James Cotton Lisa F. Wolfe James M. Walter John M. Coleman John A. Rogers The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor Journal of NeuroEngineering and Rehabilitation Rehabilitation Neuromuscular COVID-19 Peripheral nerve injury Neuropathy Brachial plexus |
| title | The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor |
| title_full | The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor |
| title_fullStr | The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor |
| title_full_unstemmed | The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor |
| title_short | The distribution of acquired peripheral nerve injuries associated with severe COVID-19 implicate a mechanism of entrapment neuropathy: a multicenter case series and clinical feasibility study of a wearable, wireless pressure sensor |
| title_sort | distribution of acquired peripheral nerve injuries associated with severe covid 19 implicate a mechanism of entrapment neuropathy a multicenter case series and clinical feasibility study of a wearable wireless pressure sensor |
| topic | Rehabilitation Neuromuscular COVID-19 Peripheral nerve injury Neuropathy Brachial plexus |
| url | https://doi.org/10.1186/s12984-022-01089-1 |
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