Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expression.

Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expression.

BACKGROUND: Gene duplication is a major driver of evolutionary innovation as it allows for an organism to elaborate its existing biological functions via specialization or diversification of initially redundant gene paralogs. Gene function can diversify in several ways. Transcription factor gene par...

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Bibliographic Details
Main Authors: Larry N Singh, Sridhar Hannenhalli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2394658?pdf=render

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