4-Hydroxyphenylacetate 3-Hydroxylase (4HPA3H): A Vigorous Monooxygenase for Versatile <i>O</i>-Hydroxylation Applications in the Biosynthesis of Phenolic Derivatives
4-Hydroxyphenylacetate 3-hydroxylase (4HPA3H) is a long-known class of two-component flavin-dependent monooxygenases from bacteria, including an oxygenase component (EC 1.14.14.9) and a reductase component (EC 1.5.1.36), with the latter being accountable for delivering the cofactor (reduced flavin)...
Main Authors: | Ping Sun, Shuping Xu, Yuan Tian, Pengcheng Chen, Dan Wu, Pu Zheng |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-01-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/25/2/1222 |
Similar Items
-
Advances in 4-Hydroxyphenylacetate-3-hydroxylase Monooxygenase
by: Kai Yang, et al.
Published: (2023-09-01) -
A single amino acid substitution in aromatic hydroxylase (HpaB) of Escherichia coli alters substrate specificity of the structural isomers of hydroxyphenylacetate
by: Hanseol Kim, et al.
Published: (2020-05-01) -
Modification of the 4-Hydroxyphenylacetate-3-hydroxylase Substrate Pocket to Increase Activity towards Resveratrol
by: Qianchao Zhang, et al.
Published: (2023-07-01) -
Optimization of the Biosynthesis of B-Ring <i>Ortho</i>-Hydroxy Lated Flavonoids Using the 4-Hydroxyphenylacetate 3-Hydroxylase Complex (HpaBC) of <i>Escherichia coli</i>
by: Longji Wang, et al.
Published: (2021-05-01) -
Monooxygenases and Antibiotic Resistance: A Focus on Carbapenems
by: Daniela Minerdi, et al.
Published: (2023-10-01)