Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention
Anemia is a frequent systemic complication and extra-intestinal manifestation of inflammatory bowel diseases (IBD). Despite significant progress in IBD treatment, late diagnosis and insufficient correction of concomitant anemia remain a problem in routine clinical practice. The review describes the...
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| Format: | Article |
| Language: | Russian |
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MONIKI
2020-01-01
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| Series: | Alʹmanah Kliničeskoj Mediciny |
| Subjects: | |
| Online Access: | https://www.almclinmed.ru/jour/article/view/1208 |
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| author | I. V. Gubonina O. B. Shchukina N. I. Stuklov T. V. Gaponova D. I. Abdulganieva O. V. Knyazev N. S. Gubonina |
| author_facet | I. V. Gubonina O. B. Shchukina N. I. Stuklov T. V. Gaponova D. I. Abdulganieva O. V. Knyazev N. S. Gubonina |
| author_sort | I. V. Gubonina |
| collection | DOAJ |
| description | Anemia is a frequent systemic complication and extra-intestinal manifestation of inflammatory bowel diseases (IBD). Despite significant progress in IBD treatment, late diagnosis and insufficient correction of concomitant anemia remain a problem in routine clinical practice. The review describes the main pathophysiological mechanisms of IBD-associated anemia, such as iron deficiency, chronic inflammation (anemia of chronic disease) and B9 and B12 deficiencies. The authors highlight the main diagnostic principles of these conditions, present the strategy for their differential diagnosis, describe the state-of-theart approaches to the correction of iron-deficient anemia in IBD, and delineate the role of oral and parenteral medications for replacement therapy. Optimal treatment goals and prevention methods of an iron-deficient condition are given. Special attention is focused on the principles on red cell mass transfusions in acute massive blood loss. The authors describe the main differentiating features of anemia of chronic disease and its treatment in IBD patients with various grades of the inflammation. The paper contains the indications and treatment regimens for B12 and foliate-deficient anemia with consideration of the IBD course. The authors of the article are members of the Working Group of the Russian Society on the study of IBD and believe that the literature analysis performed would allow for its use to issue the Russian clinical guidelines on the management of patients with anemia in ulcerative colitis and Crohn's disease. |
| first_indexed | 2024-12-16T18:45:16Z |
| format | Article |
| id | doaj.art-6655bea97ea24abe9891fb0568cfa0c1 |
| institution | Directory Open Access Journal |
| issn | 2072-0505 2587-9294 |
| language | Russian |
| last_indexed | 2024-12-16T18:45:16Z |
| publishDate | 2020-01-01 |
| publisher | MONIKI |
| record_format | Article |
| series | Alʹmanah Kliničeskoj Mediciny |
| spelling | doaj.art-6655bea97ea24abe9891fb0568cfa0c12022-12-21T22:20:51ZrusMONIKIAlʹmanah Kliničeskoj Mediciny2072-05052587-92942020-01-0147872173210.18786/2072-0505-2019-47-078698Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and preventionI. V. Gubonina0O. B. Shchukina1N. I. Stuklov2T. V. Gaponova3D. I. Abdulganieva4O. V. Knyazev5N. S. Gubonina6Military Medical Academy named after S.M. KirovAcademician I.P. Pavlov First St. Petersburg State Medical UniversityPeoples' Friendship University of Russia (RUDN University)National Research Center for HematologyRepublican Clinical Hospital, Department of Health of the Republic of Tatarstan; Kazan State Medical UniversityLoginov Moscow Clinical Scientific Center, Moscow Healthcare DepartmentAlmazov National Medical Research CentreAnemia is a frequent systemic complication and extra-intestinal manifestation of inflammatory bowel diseases (IBD). Despite significant progress in IBD treatment, late diagnosis and insufficient correction of concomitant anemia remain a problem in routine clinical practice. The review describes the main pathophysiological mechanisms of IBD-associated anemia, such as iron deficiency, chronic inflammation (anemia of chronic disease) and B9 and B12 deficiencies. The authors highlight the main diagnostic principles of these conditions, present the strategy for their differential diagnosis, describe the state-of-theart approaches to the correction of iron-deficient anemia in IBD, and delineate the role of oral and parenteral medications for replacement therapy. Optimal treatment goals and prevention methods of an iron-deficient condition are given. Special attention is focused on the principles on red cell mass transfusions in acute massive blood loss. The authors describe the main differentiating features of anemia of chronic disease and its treatment in IBD patients with various grades of the inflammation. The paper contains the indications and treatment regimens for B12 and foliate-deficient anemia with consideration of the IBD course. The authors of the article are members of the Working Group of the Russian Society on the study of IBD and believe that the literature analysis performed would allow for its use to issue the Russian clinical guidelines on the management of patients with anemia in ulcerative colitis and Crohn's disease.https://www.almclinmed.ru/jour/article/view/1208anemia diagnosisiron-deficient anemiaanemia of chronic diseaseinflammatory bowel diseasesulcerative colitiscrohn's diseasetreatment of anemia |
| spellingShingle | I. V. Gubonina O. B. Shchukina N. I. Stuklov T. V. Gaponova D. I. Abdulganieva O. V. Knyazev N. S. Gubonina Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention Alʹmanah Kliničeskoj Mediciny anemia diagnosis iron-deficient anemia anemia of chronic disease inflammatory bowel diseases ulcerative colitis crohn's disease treatment of anemia |
| title | Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention |
| title_full | Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention |
| title_fullStr | Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention |
| title_full_unstemmed | Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention |
| title_short | Anemia in inflammatory bowel diseases: the approaches to its diagnosis, treatment and prevention |
| title_sort | anemia in inflammatory bowel diseases the approaches to its diagnosis treatment and prevention |
| topic | anemia diagnosis iron-deficient anemia anemia of chronic disease inflammatory bowel diseases ulcerative colitis crohn's disease treatment of anemia |
| url | https://www.almclinmed.ru/jour/article/view/1208 |
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