EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C
Objective: In the second half of April 2020, a new syndrome associated with SARS-CoV-2 infection,”multisystem inflammatory syndrome in children” (MIS-C), was defined by the World Health Organization.However, the risk factors that predispose some children to develop this inflammatory response are poo...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-11-01
|
| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137921011445 |
| _version_ | 1818931238052823040 |
|---|---|
| author | Fatma Burçin KURTİPEK Ahmet Vedat KAVURT Elif ÇELİKEL Emel UYAR Emine AZAK Oktay PERK Neşe Yaralı Namık Yaşar Özbek |
| author_facet | Fatma Burçin KURTİPEK Ahmet Vedat KAVURT Elif ÇELİKEL Emel UYAR Emine AZAK Oktay PERK Neşe Yaralı Namık Yaşar Özbek |
| author_sort | Fatma Burçin KURTİPEK |
| collection | DOAJ |
| description | Objective: In the second half of April 2020, a new syndrome associated with SARS-CoV-2 infection,”multisystem inflammatory syndrome in children” (MIS-C), was defined by the World Health Organization.However, the risk factors that predispose some children to develop this inflammatory response are poorly understood .Determining the clinical risk factors of MIS-C is important in preventing undesirable complications such as death in children. Methodology: In this study, we aimed to investigate the effect of ABO blood groups, hematological parameters (white blood cell, absolute neutrophil, absolute lymphocyte, platelet count, prothrombin time, activated partial thromboplastin time), cardiac parameters (troponin, brain natriuretic factor, electrocardiography) of patients diagnosed with MIS-C in Ankara City Hospital during the pandemic shortening fraction, ejection fraction), infectious parameters (c-reactive protein, interleukin-6, sedimentation) were analyzed retrospectively. Results: Of our 89 cases, 49 (55.1%) were group A, 3 (3.4%) were group AB (3.4%), and 11 (12.4%) were group B. 60 of our patients presented with cardiac involvement, 14 with acute abdomen, 1 with seizure, and 1 with acute kidney injury. In clinically severe cases, MPV was higher and platelet count was lower. O blood group were diagnosed with MISC at a later age. Patients with A blood group have a statistically significantly less serious course compared to other blood groups. Conclusion: In our study, we found that individuals with A blood group had MISC more frequently than other blood groups, and MISC was less severe in these patients compared to other blood groups. |
| first_indexed | 2024-12-20T04:13:25Z |
| format | Article |
| id | doaj.art-66597888b30141cca466887566bbcf35 |
| institution | Directory Open Access Journal |
| issn | 2531-1379 |
| language | English |
| last_indexed | 2024-12-20T04:13:25Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Hematology, Transfusion and Cell Therapy |
| spelling | doaj.art-66597888b30141cca466887566bbcf352022-12-21T19:53:50ZengElsevierHematology, Transfusion and Cell Therapy2531-13792021-11-0143S27S28EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-CFatma Burçin KURTİPEK0Ahmet Vedat KAVURT1Elif ÇELİKEL2Emel UYAR3Emine AZAK4Oktay PERK5Neşe Yaralı6Namık Yaşar Özbek7Ankara City HospitalAnkara City HospitalAnkara City HospitalAnkara City HospitalAnkara City HospitalAnkara City HospitalAnkara City HospitalAnkara City HospitalObjective: In the second half of April 2020, a new syndrome associated with SARS-CoV-2 infection,”multisystem inflammatory syndrome in children” (MIS-C), was defined by the World Health Organization.However, the risk factors that predispose some children to develop this inflammatory response are poorly understood .Determining the clinical risk factors of MIS-C is important in preventing undesirable complications such as death in children. Methodology: In this study, we aimed to investigate the effect of ABO blood groups, hematological parameters (white blood cell, absolute neutrophil, absolute lymphocyte, platelet count, prothrombin time, activated partial thromboplastin time), cardiac parameters (troponin, brain natriuretic factor, electrocardiography) of patients diagnosed with MIS-C in Ankara City Hospital during the pandemic shortening fraction, ejection fraction), infectious parameters (c-reactive protein, interleukin-6, sedimentation) were analyzed retrospectively. Results: Of our 89 cases, 49 (55.1%) were group A, 3 (3.4%) were group AB (3.4%), and 11 (12.4%) were group B. 60 of our patients presented with cardiac involvement, 14 with acute abdomen, 1 with seizure, and 1 with acute kidney injury. In clinically severe cases, MPV was higher and platelet count was lower. O blood group were diagnosed with MISC at a later age. Patients with A blood group have a statistically significantly less serious course compared to other blood groups. Conclusion: In our study, we found that individuals with A blood group had MISC more frequently than other blood groups, and MISC was less severe in these patients compared to other blood groups.http://www.sciencedirect.com/science/article/pii/S2531137921011445 |
| spellingShingle | Fatma Burçin KURTİPEK Ahmet Vedat KAVURT Elif ÇELİKEL Emel UYAR Emine AZAK Oktay PERK Neşe Yaralı Namık Yaşar Özbek EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C Hematology, Transfusion and Cell Therapy |
| title | EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C |
| title_full | EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C |
| title_fullStr | EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C |
| title_full_unstemmed | EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C |
| title_short | EVALUATION OF THE RELATIONSHIP OF ABO BLOOD GROUPS WITH MIS-C |
| title_sort | evaluation of the relationship of abo blood groups with mis c |
| url | http://www.sciencedirect.com/science/article/pii/S2531137921011445 |
| work_keys_str_mv | AT fatmaburcinkurtipek evaluationoftherelationshipofabobloodgroupswithmisc AT ahmetvedatkavurt evaluationoftherelationshipofabobloodgroupswithmisc AT elifcelikel evaluationoftherelationshipofabobloodgroupswithmisc AT emeluyar evaluationoftherelationshipofabobloodgroupswithmisc AT emineazak evaluationoftherelationshipofabobloodgroupswithmisc AT oktayperk evaluationoftherelationshipofabobloodgroupswithmisc AT neseyaralı evaluationoftherelationshipofabobloodgroupswithmisc AT namıkyasarozbek evaluationoftherelationshipofabobloodgroupswithmisc |