Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China
Abstract Background Headache disorders are widely prevalent and pose a considerable economic burden on individuals and society. Globally, misdiagnosis and inadequate treatment of primary headache disorders remain significant challenges, impeding the effective management of such conditions. Despite a...
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-09-01
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| Series: | The Journal of Headache and Pain |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s10194-023-01654-6 |
| _version_ | 1797452037991956480 |
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| author | Huanxian Liu Ming Dong Kaiming Liu Zhihua Jia Wei Gui Yingying Cheng Yudan Lv Kang Qu Hongru Zhao Jianjun Chen Dan Zhang Zhiliang Fan Xiaosu Yang Dongmei Hu Hongyan Xie Mingxin Li Bing Wen Sufen Chen Peng Xu Qingqing Rong Qiu He Zhanxiu Ren Fanhong Yan Heling Zhao Min Chen Tingmin Yu Hongli Qu Xingkai An Huailian Guo Xinhua Zhang Xiaoping Pan Xiaojuan Wang Shi Qiu Lvming Zhang Hongling Zhao Xin Pan Qi Wan Lanyun Yan Jing Liu Zhe Yu Mingjie Zhang Ye Ran Xun Han Shengyuan Yu Zhao Dong |
| author_facet | Huanxian Liu Ming Dong Kaiming Liu Zhihua Jia Wei Gui Yingying Cheng Yudan Lv Kang Qu Hongru Zhao Jianjun Chen Dan Zhang Zhiliang Fan Xiaosu Yang Dongmei Hu Hongyan Xie Mingxin Li Bing Wen Sufen Chen Peng Xu Qingqing Rong Qiu He Zhanxiu Ren Fanhong Yan Heling Zhao Min Chen Tingmin Yu Hongli Qu Xingkai An Huailian Guo Xinhua Zhang Xiaoping Pan Xiaojuan Wang Shi Qiu Lvming Zhang Hongling Zhao Xin Pan Qi Wan Lanyun Yan Jing Liu Zhe Yu Mingjie Zhang Ye Ran Xun Han Shengyuan Yu Zhao Dong |
| author_sort | Huanxian Liu |
| collection | DOAJ |
| description | Abstract Background Headache disorders are widely prevalent and pose a considerable economic burden on individuals and society. Globally, misdiagnosis and inadequate treatment of primary headache disorders remain significant challenges, impeding the effective management of such conditions. Despite advancements in headache management over the last decade, a need for comprehensive evaluations of the status of primary headache disorders in China regarding diagnosis and preventative treatments persists. Methods In the present study, we analyzed the established queries in the Survey of Fibromyalgia Comorbidity with Headache (SEARCH), focusing on previous diagnoses and preventative treatment regimens for primary headache disorders. This cross-sectional study encompassed adults diagnosed with primary headache disorders who sought treatment at 23 hospitals across China between September 2020 to May 2021. Results The study comprised 2,868 participants who were systematically examined. Migraine and tension-type headaches (TTH) constituted a majority of the primary headache disorders, accounting for 74.1% (2,124/2,868) and 23.3% (668/2,868) of the participants, respectively. Medication overuse headache (MOH) affected 8.1% (231/2,868) of individuals with primary headache disorders. Over half of the individuals with primary headache disorders (56.6%, 1,624/2,868) remained undiagnosed. The previously correct diagnosis rates for migraine, TTH, TACs, and MOH were 27.3% (580/2,124), 8.1% (54/668), 23.2% (13/56), and 3.5% (8/231), respectively. The misdiagnosis of “Nervous headache” was found to be the most prevalent among individuals with migraine (9.9%, 211/2,124), TTH (10.0%, 67/668), trigeminal autonomic cephalalgias (TACs) (17.9%, 10/56), and other primary headache disorders (10.0%, 2/20) respectively. Only a minor proportion of individuals with migraine (16.5%, 77/468) and TTH (4.7%, 2/43) had received preventive medication before participating in the study. Conclusions While there has been progress made in the rate of correct diagnosis of primary headache disorders in China compared to a decade ago, the prevalence of misdiagnosis and inadequate treatment of primary headaches remains a veritable issue. As such, focused efforts are essential to augment the diagnosis and preventive treatment measures related to primary headache disorders in the future. |
| first_indexed | 2024-03-09T15:02:01Z |
| format | Article |
| id | doaj.art-665a3a3a822c490ba42a3b3fa95f8c35 |
| institution | Directory Open Access Journal |
| issn | 1129-2377 |
| language | English |
| last_indexed | 2024-03-09T15:02:01Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | The Journal of Headache and Pain |
| spelling | doaj.art-665a3a3a822c490ba42a3b3fa95f8c352023-11-26T13:50:41ZengBMCThe Journal of Headache and Pain1129-23772023-09-0124111110.1186/s10194-023-01654-6Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in ChinaHuanxian Liu0Ming Dong1Kaiming Liu2Zhihua Jia3Wei Gui4Yingying Cheng5Yudan Lv6Kang Qu7Hongru Zhao8Jianjun Chen9Dan Zhang10Zhiliang Fan11Xiaosu Yang12Dongmei Hu13Hongyan Xie14Mingxin Li15Bing Wen16Sufen Chen17Peng Xu18Qingqing Rong19Qiu He20Zhanxiu Ren21Fanhong Yan22Heling Zhao23Min Chen24Tingmin Yu25Hongli Qu26Xingkai An27Huailian Guo28Xinhua Zhang29Xiaoping Pan30Xiaojuan Wang31Shi Qiu32Lvming Zhang33Hongling Zhao34Xin Pan35Qi Wan36Lanyun Yan37Jing Liu38Zhe Yu39Mingjie Zhang40Ye Ran41Xun Han42Shengyuan Yu43Zhao Dong44Department of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin UniversityDepartment of Neurology, Second Affiliated Hospital, School of Medicine, Zhejiang UniversityDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of ChinaDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin UniversityDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin UniversityDepartment of Neurology and Neuroscience Center, The First Hospital of Jilin UniversityDepartment of Neurology, The First Affiliated Hospital of Soochow UniversityDepartment of Neurology, Lishui Municipal Central HospitalDepartment of Neurology, Sir Run Run Shaw HospitalDepartment of Neurology, Xing Tai People’s HospitalDepartment of Neurology, Xiangya Hospital, Central South UniversityDepartment of Neurology, The Second Affiliated Hospital of Shandong First Medical UniversityDepartment of Neurology, The Second Affiliated Hospital of Shandong First Medical UniversityDepartment of Neurology, Qilu HospitalDepartment of Neurology, Qilu HospitalDepartment of Neurology, Changsha Central Hospital Affiliated to the University of South ChinaDepartment of Neurology, Affiliated Hospital of Jining Medical UniversityDepartment of Neurology, Affiliated Hospital of Jining Medical UniversityDepartment of Neurology, The People’s Hospital of Liaoning ProvinceDepartment of Neurology, The People’s Hospital of Liaoning ProvinceDepartment of Neurology, Linyi Jinluo HospitalDepartment of Neurology, Linyi Jinluo HospitalDepartment of Neurology, Zhengzhou University First Affiliated HospitalDepartment of Neurology, The Second Hospital of Jilin UniversityDepartment of Neurology, The First Affiliated Hospital of Xiamen UniversityDepartment of Neurology, The First Affiliated Hospital of Xiamen UniversityDepartment of Neurology, People’s Hospital, Peking UniversityDepartment of Neurology, People’s Hospital, Peking UniversityDepartment of Neurology, Guangzhou First People’s HospitalDepartment of Neurology, Guangzhou First People’s HospitalDepartment of Neurology, Aerospace Center HospitalDepartment of Neurology, Aerospace Center HospitalDepartment of Neurology, Da Lian Municipal Central HospitalDepartment of Neurology, Da Lian Municipal Central HospitalDepartment of Neurology, Jiangsu Province HospitalDepartment of Neurology, Jiangsu Province HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalDepartment of Neurology, the First Medical Center of Chinese PLA General HospitalAbstract Background Headache disorders are widely prevalent and pose a considerable economic burden on individuals and society. Globally, misdiagnosis and inadequate treatment of primary headache disorders remain significant challenges, impeding the effective management of such conditions. Despite advancements in headache management over the last decade, a need for comprehensive evaluations of the status of primary headache disorders in China regarding diagnosis and preventative treatments persists. Methods In the present study, we analyzed the established queries in the Survey of Fibromyalgia Comorbidity with Headache (SEARCH), focusing on previous diagnoses and preventative treatment regimens for primary headache disorders. This cross-sectional study encompassed adults diagnosed with primary headache disorders who sought treatment at 23 hospitals across China between September 2020 to May 2021. Results The study comprised 2,868 participants who were systematically examined. Migraine and tension-type headaches (TTH) constituted a majority of the primary headache disorders, accounting for 74.1% (2,124/2,868) and 23.3% (668/2,868) of the participants, respectively. Medication overuse headache (MOH) affected 8.1% (231/2,868) of individuals with primary headache disorders. Over half of the individuals with primary headache disorders (56.6%, 1,624/2,868) remained undiagnosed. The previously correct diagnosis rates for migraine, TTH, TACs, and MOH were 27.3% (580/2,124), 8.1% (54/668), 23.2% (13/56), and 3.5% (8/231), respectively. The misdiagnosis of “Nervous headache” was found to be the most prevalent among individuals with migraine (9.9%, 211/2,124), TTH (10.0%, 67/668), trigeminal autonomic cephalalgias (TACs) (17.9%, 10/56), and other primary headache disorders (10.0%, 2/20) respectively. Only a minor proportion of individuals with migraine (16.5%, 77/468) and TTH (4.7%, 2/43) had received preventive medication before participating in the study. Conclusions While there has been progress made in the rate of correct diagnosis of primary headache disorders in China compared to a decade ago, the prevalence of misdiagnosis and inadequate treatment of primary headaches remains a veritable issue. As such, focused efforts are essential to augment the diagnosis and preventive treatment measures related to primary headache disorders in the future.https://doi.org/10.1186/s10194-023-01654-6DiagnosisTreatmentPrimary headache disordersMigraineTension-type headache |
| spellingShingle | Huanxian Liu Ming Dong Kaiming Liu Zhihua Jia Wei Gui Yingying Cheng Yudan Lv Kang Qu Hongru Zhao Jianjun Chen Dan Zhang Zhiliang Fan Xiaosu Yang Dongmei Hu Hongyan Xie Mingxin Li Bing Wen Sufen Chen Peng Xu Qingqing Rong Qiu He Zhanxiu Ren Fanhong Yan Heling Zhao Min Chen Tingmin Yu Hongli Qu Xingkai An Huailian Guo Xinhua Zhang Xiaoping Pan Xiaojuan Wang Shi Qiu Lvming Zhang Hongling Zhao Xin Pan Qi Wan Lanyun Yan Jing Liu Zhe Yu Mingjie Zhang Ye Ran Xun Han Shengyuan Yu Zhao Dong Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China The Journal of Headache and Pain Diagnosis Treatment Primary headache disorders Migraine Tension-type headache |
| title | Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China |
| title_full | Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China |
| title_fullStr | Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China |
| title_full_unstemmed | Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China |
| title_short | Status of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China |
| title_sort | status of diagnosis and preventative treatment for primary headache disorders real world data of unmet needs in china |
| topic | Diagnosis Treatment Primary headache disorders Migraine Tension-type headache |
| url | https://doi.org/10.1186/s10194-023-01654-6 |
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