A matter of origin - identification of SEMA3A, BGLAP, SPP1 and PHEX as distinctive molecular features between bone site-specific human osteoblasts on transcription level

A matter of origin - identification of SEMA3A, BGLAP, SPP1 and PHEX as distinctive molecular features between bone site-specific human osteoblasts on transcription level

In oral and maxillofacial bone reconstruction, autografts from the iliac crest represent the gold standard due to their superior clinical performance, compared to autografts derived from other extraoral regions. Thus, the aim of our study was to identify putative differences between osteoblasts deri...

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Bibliographic Details
Main Authors: Weiping Zhang, Sibylle Rau, Konstantinos Kotzagiorgis, René Rothweiler, Susanne Nahles, Eric Gottwald, Bernd Rolauffs, Thorsten Steinberg, Katja Nelson, Brigitte Altmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
bone grafts
3D-microchip culture
in vitro model
gene expression analysis
alveolar bone
iliac crest
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.918866/full

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