Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat
Abstract An adult domestic short‐haired feline leukemia virus‐infected cat was referred for kidney failure and worsening anemia requiring transfusions. ABC blood typing was performed with an immunochromatographic strip assay at different occasions. Gel column systems were used for the major and mino...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | Journal of Veterinary Internal Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jvim.16927 |
| _version_ | 1797349501393960960 |
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| author | Argyrios Ginoudis Bertrand Canard Alexandra Kehl Urs Giger Christos Koutinas Stella Christoforaki Erasmia Smyroglou Zoe Polizopoulou Mathios E. Mylonakis |
| author_facet | Argyrios Ginoudis Bertrand Canard Alexandra Kehl Urs Giger Christos Koutinas Stella Christoforaki Erasmia Smyroglou Zoe Polizopoulou Mathios E. Mylonakis |
| author_sort | Argyrios Ginoudis |
| collection | DOAJ |
| description | Abstract An adult domestic short‐haired feline leukemia virus‐infected cat was referred for kidney failure and worsening anemia requiring transfusions. ABC blood typing was performed with an immunochromatographic strip assay at different occasions. Gel column systems were used for the major and minor crossmatching tests, and anti‐A and anti‐B titers were determined. No discrete A or B bands appeared on the immunochromatographic strips at any time point for the recipient cat. The recipient's plasma agglutinated RBCs from tested type A and B cats. The recipient's RBCs appeared compatible with plasma from 1 type A and 2 B donors, and incompatible with plasma from another type A cat. Genotyping of recipient blood revealed a single homozygous c.179G>T CMAH variant predicting a blood type B. These studies suggest an unusual weak type B or missing all ABC antigens. The latter resembles the exceedingly rare Bombay phenotype in the human ABO blood group system. |
| first_indexed | 2024-03-08T12:31:15Z |
| format | Article |
| id | doaj.art-665ba09e9ee54f8889abec49b3c1dacd |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-03-08T12:31:15Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-665ba09e9ee54f8889abec49b3c1dacd2024-01-22T02:05:50ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762024-01-0138135836210.1111/jvim.16927Discordance between ABC blood phenotype and genotype in a domestic short‐haired catArgyrios Ginoudis0Bertrand Canard1Alexandra Kehl2Urs Giger3Christos Koutinas4Stella Christoforaki5Erasmia Smyroglou6Zoe Polizopoulou7Mathios E. Mylonakis8Diagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki GreeceAlvedia Limonest FranceLaboklin GmbH & Co. KG Bad Kissingen GermanyVetsuisse Faculty University of Zürich Zürich SwitzerlandCompanion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki GreeceCompanion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki GreeceDiagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki GreeceDiagnostic Laboratory, School of Veterinary Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki GreeceCompanion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki GreeceAbstract An adult domestic short‐haired feline leukemia virus‐infected cat was referred for kidney failure and worsening anemia requiring transfusions. ABC blood typing was performed with an immunochromatographic strip assay at different occasions. Gel column systems were used for the major and minor crossmatching tests, and anti‐A and anti‐B titers were determined. No discrete A or B bands appeared on the immunochromatographic strips at any time point for the recipient cat. The recipient's plasma agglutinated RBCs from tested type A and B cats. The recipient's RBCs appeared compatible with plasma from 1 type A and 2 B donors, and incompatible with plasma from another type A cat. Genotyping of recipient blood revealed a single homozygous c.179G>T CMAH variant predicting a blood type B. These studies suggest an unusual weak type B or missing all ABC antigens. The latter resembles the exceedingly rare Bombay phenotype in the human ABO blood group system.https://doi.org/10.1111/jvim.16927alloantibodiesblood typingBombay phenotypecrossmatchfelineH antigen |
| spellingShingle | Argyrios Ginoudis Bertrand Canard Alexandra Kehl Urs Giger Christos Koutinas Stella Christoforaki Erasmia Smyroglou Zoe Polizopoulou Mathios E. Mylonakis Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat Journal of Veterinary Internal Medicine alloantibodies blood typing Bombay phenotype crossmatch feline H antigen |
| title | Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat |
| title_full | Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat |
| title_fullStr | Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat |
| title_full_unstemmed | Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat |
| title_short | Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat |
| title_sort | discordance between abc blood phenotype and genotype in a domestic short haired cat |
| topic | alloantibodies blood typing Bombay phenotype crossmatch feline H antigen |
| url | https://doi.org/10.1111/jvim.16927 |
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