Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View
<i>Aeromonas</i> species often cause disease in farmed fish and are responsible for causing significant economic losses worldwide. Although vaccination is the ideal method to prevent infectious diseases, there are still very few vaccines commercially available in the aquaculture field. C...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/11/2/163 |
| _version_ | 1797483399989952512 |
|---|---|
| author | Carla Pereira João Duarte Pedro Costa Márcia Braz Adelaide Almeida |
| author_facet | Carla Pereira João Duarte Pedro Costa Márcia Braz Adelaide Almeida |
| author_sort | Carla Pereira |
| collection | DOAJ |
| description | <i>Aeromonas</i> species often cause disease in farmed fish and are responsible for causing significant economic losses worldwide. Although vaccination is the ideal method to prevent infectious diseases, there are still very few vaccines commercially available in the aquaculture field. Currently, aquaculture production relies heavily on antibiotics, contributing to the global issue of the emergence of antimicrobial-resistant bacteria and resistance genes. Therefore, it is essential to develop effective alternatives to antibiotics to reduce their use in aquaculture systems. Bacteriophage (or phage) therapy is a promising approach to control pathogenic bacteria in farmed fish that requires a heavy understanding of certain factors such as the selection of phages, the multiplicity of infection that produces the best bacterial inactivation, bacterial resistance, safety, the host’s immune response, administration route, phage stability and influence. This review focuses on the need to advance phage therapy research in aquaculture, its efficiency as an antimicrobial strategy and the critical aspects to successfully apply this therapy to control <i>Aeromonas</i> infection in fish. |
| first_indexed | 2024-03-09T22:47:22Z |
| format | Article |
| id | doaj.art-665ce3abbd234e70baa007d43b551506 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-09T22:47:22Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-665ce3abbd234e70baa007d43b5515062023-11-23T18:27:29ZengMDPI AGAntibiotics2079-63822022-01-0111216310.3390/antibiotics11020163Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative ViewCarla Pereira0João Duarte1Pedro Costa2Márcia Braz3Adelaide Almeida4Department of Biology and CESAM, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Biology and CESAM, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Biology and CESAM, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Biology and CESAM, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, PortugalDepartment of Biology and CESAM, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal<i>Aeromonas</i> species often cause disease in farmed fish and are responsible for causing significant economic losses worldwide. Although vaccination is the ideal method to prevent infectious diseases, there are still very few vaccines commercially available in the aquaculture field. Currently, aquaculture production relies heavily on antibiotics, contributing to the global issue of the emergence of antimicrobial-resistant bacteria and resistance genes. Therefore, it is essential to develop effective alternatives to antibiotics to reduce their use in aquaculture systems. Bacteriophage (or phage) therapy is a promising approach to control pathogenic bacteria in farmed fish that requires a heavy understanding of certain factors such as the selection of phages, the multiplicity of infection that produces the best bacterial inactivation, bacterial resistance, safety, the host’s immune response, administration route, phage stability and influence. This review focuses on the need to advance phage therapy research in aquaculture, its efficiency as an antimicrobial strategy and the critical aspects to successfully apply this therapy to control <i>Aeromonas</i> infection in fish.https://www.mdpi.com/2079-6382/11/2/163phage therapy<i>Aeromonas</i> speciesbacterial infectionsaquaculturefish |
| spellingShingle | Carla Pereira João Duarte Pedro Costa Márcia Braz Adelaide Almeida Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View Antibiotics phage therapy <i>Aeromonas</i> species bacterial infections aquaculture fish |
| title | Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View |
| title_full | Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View |
| title_fullStr | Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View |
| title_full_unstemmed | Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View |
| title_short | Bacteriophages in the Control of <i>Aeromonas</i> sp. in Aquaculture Systems: An Integrative View |
| title_sort | bacteriophages in the control of i aeromonas i sp in aquaculture systems an integrative view |
| topic | phage therapy <i>Aeromonas</i> species bacterial infections aquaculture fish |
| url | https://www.mdpi.com/2079-6382/11/2/163 |
| work_keys_str_mv | AT carlapereira bacteriophagesinthecontrolofiaeromonasispinaquaculturesystemsanintegrativeview AT joaoduarte bacteriophagesinthecontrolofiaeromonasispinaquaculturesystemsanintegrativeview AT pedrocosta bacteriophagesinthecontrolofiaeromonasispinaquaculturesystemsanintegrativeview AT marciabraz bacteriophagesinthecontrolofiaeromonasispinaquaculturesystemsanintegrativeview AT adelaidealmeida bacteriophagesinthecontrolofiaeromonasispinaquaculturesystemsanintegrativeview |