Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy
This mini-review summarizes the most recent progress concerning the use of surface-enhanced Raman spectroscopy (SERS) for the detection and characterization of antibiotic-resistant bacteria. We first discussed the design and synthesis of various types of nanomaterials that can be used as the SERS-ac...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-09-01
|
| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2079-4991/8/10/762 |
| _version_ | 1818907316125171712 |
|---|---|
| author | Kaidi Wang Shenmiao Li Marlen Petersen Shuo Wang Xiaonan Lu |
| author_facet | Kaidi Wang Shenmiao Li Marlen Petersen Shuo Wang Xiaonan Lu |
| author_sort | Kaidi Wang |
| collection | DOAJ |
| description | This mini-review summarizes the most recent progress concerning the use of surface-enhanced Raman spectroscopy (SERS) for the detection and characterization of antibiotic-resistant bacteria. We first discussed the design and synthesis of various types of nanomaterials that can be used as the SERS-active substrates for biosensing trace levels of antibiotic-resistant bacteria. We then reviewed the tandem-SERS strategy of integrating a separation element/platform with SERS sensing to achieve the detection of antibiotic-resistant bacteria in the environmental, agri-food, and clinical samples. Finally, we demonstrated the application of using SERS to investigate bacterial antibiotic resistance and susceptibility as well as the working mechanism of antibiotics based on spectral fingerprinting of the whole cells. |
| first_indexed | 2024-12-19T21:53:11Z |
| format | Article |
| id | doaj.art-665f158ef616424eaee2f6ec7207c306 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-19T21:53:11Z |
| publishDate | 2018-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-665f158ef616424eaee2f6ec7207c3062022-12-21T20:04:20ZengMDPI AGNanomaterials2079-49912018-09-0181076210.3390/nano8100762nano8100762Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman SpectroscopyKaidi Wang0Shenmiao Li1Marlen Petersen2Shuo Wang3Xiaonan Lu4Food, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T1Z4, CanadaFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T1Z4, CanadaFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T1Z4, CanadaTianjin Key Laboratory of Food Science and Health, School of Medicine, Nankai University, Tianjin 300371, ChinaFood, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC V6T1Z4, CanadaThis mini-review summarizes the most recent progress concerning the use of surface-enhanced Raman spectroscopy (SERS) for the detection and characterization of antibiotic-resistant bacteria. We first discussed the design and synthesis of various types of nanomaterials that can be used as the SERS-active substrates for biosensing trace levels of antibiotic-resistant bacteria. We then reviewed the tandem-SERS strategy of integrating a separation element/platform with SERS sensing to achieve the detection of antibiotic-resistant bacteria in the environmental, agri-food, and clinical samples. Finally, we demonstrated the application of using SERS to investigate bacterial antibiotic resistance and susceptibility as well as the working mechanism of antibiotics based on spectral fingerprinting of the whole cells.http://www.mdpi.com/2079-4991/8/10/762SERSchemometricsresistancebiosensingrapid detection |
| spellingShingle | Kaidi Wang Shenmiao Li Marlen Petersen Shuo Wang Xiaonan Lu Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy Nanomaterials SERS chemometrics resistance biosensing rapid detection |
| title | Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy |
| title_full | Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy |
| title_fullStr | Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy |
| title_full_unstemmed | Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy |
| title_short | Detection and Characterization of Antibiotic-Resistant Bacteria Using Surface-Enhanced Raman Spectroscopy |
| title_sort | detection and characterization of antibiotic resistant bacteria using surface enhanced raman spectroscopy |
| topic | SERS chemometrics resistance biosensing rapid detection |
| url | http://www.mdpi.com/2079-4991/8/10/762 |
| work_keys_str_mv | AT kaidiwang detectionandcharacterizationofantibioticresistantbacteriausingsurfaceenhancedramanspectroscopy AT shenmiaoli detectionandcharacterizationofantibioticresistantbacteriausingsurfaceenhancedramanspectroscopy AT marlenpetersen detectionandcharacterizationofantibioticresistantbacteriausingsurfaceenhancedramanspectroscopy AT shuowang detectionandcharacterizationofantibioticresistantbacteriausingsurfaceenhancedramanspectroscopy AT xiaonanlu detectionandcharacterizationofantibioticresistantbacteriausingsurfaceenhancedramanspectroscopy |