Use of eggshells as a raw material for production of calcium preparations

The kinetics of calcium release from tablets obtained from modified eggshells in the form of calcium citrate and calcium carbonate was investigated. Calcium release showed the first-order kinetics. After 30 min of the experiment, 79.93% of calcium was released from tablets obtained from modified egg...

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Main Authors: Barbara Dolińska, Marta Jelińska, Beata Szulc-Musioł, Florian Ryszka
Format: Article
Language:English
Published: Czech Academy of Agricultural Sciences 2016-08-01
Series:Czech Journal of Food Sciences
Subjects:
Online Access:https://cjfs.agriculturejournals.cz/artkey/cjf-201604-0004_use-of-eggshells-as-a-raw-material-for-production-of-calcium-preparations.php
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author Barbara Dolińska
Marta Jelińska
Beata Szulc-Musioł
Florian Ryszka
author_facet Barbara Dolińska
Marta Jelińska
Beata Szulc-Musioł
Florian Ryszka
author_sort Barbara Dolińska
collection DOAJ
description The kinetics of calcium release from tablets obtained from modified eggshells in the form of calcium citrate and calcium carbonate was investigated. Calcium release showed the first-order kinetics. After 30 min of the experiment, 79.93% of calcium was released from tablets obtained from modified eggshells in the form of calcium citrate, reaching ~100% after 3 hours. For tablets produced with calcium carbonate, these values were 7 and 60%, respectively. The half-time of calcium release from tablets containing calcium citrate was t50% = 0.5 h and for tablets containing calcium carbonate it was t50% = 2.2 h, so calcium in the form of calcium citrate was released 4 times faster. These results can be connected with different solubility of calcium salts. The hardness of tablets with calcium carbonate was by 30 N lower than the hardness of tablets with calcium citrate. It is associated with particular physicochemical properties of calcium salt. Calcium citrate can exist in several states of hydration while calcium carbonate is anhydrous. These properties have an influence on the hardness of tablets.
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spelling doaj.art-6660031157a444928f1db5e48225dc3f2023-02-23T03:28:19ZengCzech Academy of Agricultural SciencesCzech Journal of Food Sciences1212-18001805-93172016-08-0134431331710.17221/59/2016-CJFScjf-201604-0004Use of eggshells as a raw material for production of calcium preparationsBarbara Dolińska0Marta Jelińska1Beata Szulc-Musioł2Florian Ryszka3Biochefa Pharmaceutical Research and Production Plant, Sosnowiec, PolandBiochefa Pharmaceutical Research and Production Plant, Sosnowiec, PolandDepartment of Applied Pharmacy, Medical University of Silesia, Sosnowiec, PolandBiochefa Pharmaceutical Research and Production Plant, Sosnowiec, PolandThe kinetics of calcium release from tablets obtained from modified eggshells in the form of calcium citrate and calcium carbonate was investigated. Calcium release showed the first-order kinetics. After 30 min of the experiment, 79.93% of calcium was released from tablets obtained from modified eggshells in the form of calcium citrate, reaching ~100% after 3 hours. For tablets produced with calcium carbonate, these values were 7 and 60%, respectively. The half-time of calcium release from tablets containing calcium citrate was t50% = 0.5 h and for tablets containing calcium carbonate it was t50% = 2.2 h, so calcium in the form of calcium citrate was released 4 times faster. These results can be connected with different solubility of calcium salts. The hardness of tablets with calcium carbonate was by 30 N lower than the hardness of tablets with calcium citrate. It is associated with particular physicochemical properties of calcium salt. Calcium citrate can exist in several states of hydration while calcium carbonate is anhydrous. These properties have an influence on the hardness of tablets.https://cjfs.agriculturejournals.cz/artkey/cjf-201604-0004_use-of-eggshells-as-a-raw-material-for-production-of-calcium-preparations.phpcalcium releasecalcium carbonatecalcium citrate
spellingShingle Barbara Dolińska
Marta Jelińska
Beata Szulc-Musioł
Florian Ryszka
Use of eggshells as a raw material for production of calcium preparations
Czech Journal of Food Sciences
calcium release
calcium carbonate
calcium citrate
title Use of eggshells as a raw material for production of calcium preparations
title_full Use of eggshells as a raw material for production of calcium preparations
title_fullStr Use of eggshells as a raw material for production of calcium preparations
title_full_unstemmed Use of eggshells as a raw material for production of calcium preparations
title_short Use of eggshells as a raw material for production of calcium preparations
title_sort use of eggshells as a raw material for production of calcium preparations
topic calcium release
calcium carbonate
calcium citrate
url https://cjfs.agriculturejournals.cz/artkey/cjf-201604-0004_use-of-eggshells-as-a-raw-material-for-production-of-calcium-preparations.php
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AT beataszulcmusioł useofeggshellsasarawmaterialforproductionofcalciumpreparations
AT florianryszka useofeggshellsasarawmaterialforproductionofcalciumpreparations