Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus
AIM: To observe the clinical effect of trabeculectomy combined with dexamethasone iontophoresis in the treatment of acute angle-closure glaucoma(PACG)with diabetes mellitus.<p>METHODS: Totally 42 eyes of 42 patients with acute PACG combined with diabetes in our hospital were selected and divid...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2019-11-01
|
| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2019/11/201911022.pdf |
| _version_ | 1818300149446737920 |
|---|---|
| author | Cheng-Zhang Qiu Yong-Dong Chen Gao-Ming Zhang |
| author_facet | Cheng-Zhang Qiu Yong-Dong Chen Gao-Ming Zhang |
| author_sort | Cheng-Zhang Qiu |
| collection | DOAJ |
| description | AIM: To observe the clinical effect of trabeculectomy combined with dexamethasone iontophoresis in the treatment of acute angle-closure glaucoma(PACG)with diabetes mellitus.<p>METHODS: Totally 42 eyes of 42 patients with acute PACG combined with diabetes in our hospital were selected and divided into trabeculectomy combined with iontophoresis group(group A)and trabeculectomy combined with peribulbar injection of methylprednisolone group(group B)according to different ways of controlling inflammation after surgery. Intraocular pressure, anterior chamber inflammation and complications before and after surgery were compared between the two groups.<p>RESULTS: The intraocular pressure of the two groups after surgery was significantly improved compared with that before surgery, and the difference was statistically significant(<i>P</i><0.05). Postoperative anterior chamber inflammation was well controlled in both groups without statistical significance(<i>P</i>>0.05). In terms of complications, group A was significantly superior to group B.<p>CONCLUSION: Trabeculectomy combined with dexamethasone iontophoresis or peribulbar injection of methylprednisolone can effectively control postoperative intraocular pressure and anterior chamber inflammation in patients with acute angle-closure glaucoma complicated with diabetes mellitus. Among them, the effect of combined dexamethasone iontophoresis in reducing complications is better and patients suffer less pain. |
| first_indexed | 2024-12-13T05:02:32Z |
| format | Article |
| id | doaj.art-6662d42ca35c452189d2f6e6609a85c9 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-13T05:02:32Z |
| publishDate | 2019-11-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-6662d42ca35c452189d2f6e6609a85c92022-12-21T23:58:45ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232019-11-0119111912191410.3980/j.issn.1672-5123.2019.11.22Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitusCheng-Zhang Qiu0Yong-Dong Chen1Gao-Ming Zhang2Beilonggang Eye Hospital, Yancheng 224033, Jiangsu Province, ChinaBeilonggang Eye Hospital, Yancheng 224033, Jiangsu Province, ChinaDepartment of Ophthalmology, Jiangyin Hospital of Traditional Chinese Medicine, Jiangyin 214400, Jiangsu Province, ChinaAIM: To observe the clinical effect of trabeculectomy combined with dexamethasone iontophoresis in the treatment of acute angle-closure glaucoma(PACG)with diabetes mellitus.<p>METHODS: Totally 42 eyes of 42 patients with acute PACG combined with diabetes in our hospital were selected and divided into trabeculectomy combined with iontophoresis group(group A)and trabeculectomy combined with peribulbar injection of methylprednisolone group(group B)according to different ways of controlling inflammation after surgery. Intraocular pressure, anterior chamber inflammation and complications before and after surgery were compared between the two groups.<p>RESULTS: The intraocular pressure of the two groups after surgery was significantly improved compared with that before surgery, and the difference was statistically significant(<i>P</i><0.05). Postoperative anterior chamber inflammation was well controlled in both groups without statistical significance(<i>P</i>>0.05). In terms of complications, group A was significantly superior to group B.<p>CONCLUSION: Trabeculectomy combined with dexamethasone iontophoresis or peribulbar injection of methylprednisolone can effectively control postoperative intraocular pressure and anterior chamber inflammation in patients with acute angle-closure glaucoma complicated with diabetes mellitus. Among them, the effect of combined dexamethasone iontophoresis in reducing complications is better and patients suffer less pain.http://ies.ijo.cn/cn_publish/2019/11/201911022.pdftrabeculectomyiontophoresisweek of ball injectionacute angle-closure glaucomadiabetes |
| spellingShingle | Cheng-Zhang Qiu Yong-Dong Chen Gao-Ming Zhang Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus Guoji Yanke Zazhi trabeculectomy iontophoresis week of ball injection acute angle-closure glaucoma diabetes |
| title | Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus |
| title_full | Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus |
| title_fullStr | Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus |
| title_full_unstemmed | Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus |
| title_short | Clinical observation of trabeculectomy combined with Dexamethasone iontophoresis in the treatment of acute PACG complicated with diabetes mellitus |
| title_sort | clinical observation of trabeculectomy combined with dexamethasone iontophoresis in the treatment of acute pacg complicated with diabetes mellitus |
| topic | trabeculectomy iontophoresis week of ball injection acute angle-closure glaucoma diabetes |
| url | http://ies.ijo.cn/cn_publish/2019/11/201911022.pdf |
| work_keys_str_mv | AT chengzhangqiu clinicalobservationoftrabeculectomycombinedwithdexamethasoneiontophoresisinthetreatmentofacutepacgcomplicatedwithdiabetesmellitus AT yongdongchen clinicalobservationoftrabeculectomycombinedwithdexamethasoneiontophoresisinthetreatmentofacutepacgcomplicatedwithdiabetesmellitus AT gaomingzhang clinicalobservationoftrabeculectomycombinedwithdexamethasoneiontophoresisinthetreatmentofacutepacgcomplicatedwithdiabetesmellitus |