Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells

Detrimental Actions of Chlorinated Nucleosides on the Function and Viability of Insulin-Producing Cells

Neutrophils are innate immune cells that play a key role in pathogen clearance. They contribute to inflammatory diseases, including diabetes, by releasing pro-inflammatory cytokines, reactive oxygen species, and extracellular traps (NETs). NETs contain a DNA backbone and catalytically active myelope...

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Bibliographic Details
Main Authors: Inga Sileikaite-Morvaközi, William H. Hansen, Michael J. Davies, Thomas Mandrup-Poulsen, Clare L. Hawkins
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
chlorinated nucleosides
myeloperoxidase
hypochlorous acid
inflammation
diabetes
Online Access:https://www.mdpi.com/1422-0067/24/19/14585

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