Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants
Background: Septicaemia is a leading cause of morbidity and mortality of infant’s and childerens espicially in first week of their life, both in developed and underdeveloped countries.The aim of this research was to study of bacterial agents causing septicaemia and to determine their antib...
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| Format: | Article |
| Language: | English |
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Bushehr University of Medical Sciences
2014-05-01
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| Series: | Iranian South Medical Journal |
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| Online Access: | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-446&slc_lang=en&sid=1 |
| _version_ | 1819177804105777152 |
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| author | Mohammad Kazem Sharifi Yazdi Mohammad Taghi Haghi Ashtiani Bahram Nikmanesh Mohammad Mehdi Soltan Dallal |
| author_facet | Mohammad Kazem Sharifi Yazdi Mohammad Taghi Haghi Ashtiani Bahram Nikmanesh Mohammad Mehdi Soltan Dallal |
| author_sort | Mohammad Kazem Sharifi Yazdi |
| collection | DOAJ |
| description | Background: Septicaemia is a leading cause of morbidity and mortality of infant’s and childerens espicially in first week of their life, both in developed and underdeveloped countries.The aim of this research was to study of bacterial agents causing septicaemia and to determine their antibiotic suseptibility patternes. Materials and Methods : This was a descriptive study, it was performed during eight months from October 2011 till May 2011.In total 216 blood culture samples of children suspected of septicaemia in children health centre hospital were send to the laboratory for investigation. The bacterial identification was carried out by culturing and conventional biomedical tests. The antibiotic sensitivity tests were performed by disk diffusion method. These data are analyzed by SPSS and the results Expressed as relative frequencies. Results: Out of 216 tested samples 55(25.6%) were positive and 161 (74.54%) negative. The dominated bacteria was Escherichia coli (31.42%), followed by Staphylococcus aureus (22.86 %), Klebsiella pneumonia (20%)), Staphylococcus epidermidis (14.28%), Streptococcus pneumonia (2.86%), Salmonella typhi (2.86%), Enterobacter cloacae (2.86%) and Stenotrophomonas maltophilia (2.86%). In general gram-negative bacteria were isolated more than gram-positive. Staphylococcus bacteria were more resistant to antibiotics than other isolated bacteria, and were 100% resistant to penicillin. The enterobacteriaceae were more sensitive to norfloxacin, amikacin, tobramycin, and they were 100% resistant to ampicillin. Conclusion: The results obtained in this study showed that gram-negative bacteria are more responsible in septicaemia in children ward, and norfloxacin is the more effective antibiotic in comparison with others. |
| first_indexed | 2024-12-22T21:32:28Z |
| format | Article |
| id | doaj.art-666bb77a257d4c3082227ea190f8e3da |
| institution | Directory Open Access Journal |
| issn | 1735-4374 1735-6954 |
| language | English |
| last_indexed | 2024-12-22T21:32:28Z |
| publishDate | 2014-05-01 |
| publisher | Bushehr University of Medical Sciences |
| record_format | Article |
| series | Iranian South Medical Journal |
| spelling | doaj.art-666bb77a257d4c3082227ea190f8e3da2022-12-21T18:11:52ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542014-05-01172223232Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infantsMohammad Kazem Sharifi Yazdi0Mohammad Taghi Haghi Ashtiani1Bahram Nikmanesh2Mohammad Mehdi Soltan Dallal3 Department of Medical Laboratory Sciences, School of Paramedical Sciences, Tehran University of Medical Sciences, Tehran, IRAN. Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, IRAN. Background: Septicaemia is a leading cause of morbidity and mortality of infant’s and childerens espicially in first week of their life, both in developed and underdeveloped countries.The aim of this research was to study of bacterial agents causing septicaemia and to determine their antibiotic suseptibility patternes. Materials and Methods : This was a descriptive study, it was performed during eight months from October 2011 till May 2011.In total 216 blood culture samples of children suspected of septicaemia in children health centre hospital were send to the laboratory for investigation. The bacterial identification was carried out by culturing and conventional biomedical tests. The antibiotic sensitivity tests were performed by disk diffusion method. These data are analyzed by SPSS and the results Expressed as relative frequencies. Results: Out of 216 tested samples 55(25.6%) were positive and 161 (74.54%) negative. The dominated bacteria was Escherichia coli (31.42%), followed by Staphylococcus aureus (22.86 %), Klebsiella pneumonia (20%)), Staphylococcus epidermidis (14.28%), Streptococcus pneumonia (2.86%), Salmonella typhi (2.86%), Enterobacter cloacae (2.86%) and Stenotrophomonas maltophilia (2.86%). In general gram-negative bacteria were isolated more than gram-positive. Staphylococcus bacteria were more resistant to antibiotics than other isolated bacteria, and were 100% resistant to penicillin. The enterobacteriaceae were more sensitive to norfloxacin, amikacin, tobramycin, and they were 100% resistant to ampicillin. Conclusion: The results obtained in this study showed that gram-negative bacteria are more responsible in septicaemia in children ward, and norfloxacin is the more effective antibiotic in comparison with others.http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-446&slc_lang=en&sid=1septicaemia infants bacterial agent antibiotic resistance |
| spellingShingle | Mohammad Kazem Sharifi Yazdi Mohammad Taghi Haghi Ashtiani Bahram Nikmanesh Mohammad Mehdi Soltan Dallal Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants Iranian South Medical Journal septicaemia infants bacterial agent antibiotic resistance |
| title | Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants |
| title_full | Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants |
| title_fullStr | Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants |
| title_full_unstemmed | Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants |
| title_short | Comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants |
| title_sort | comparison of antibiotic resistance of bacterial agents associated in septicaemia in children and infants |
| topic | septicaemia infants bacterial agent antibiotic resistance |
| url | http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-446&slc_lang=en&sid=1 |
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