Impact of tramadol and morphine abuse on the activities of acetylcholine esterase, Na+/K+-ATPase and related parameters in cerebral cortices of male adult rats

Objective: To determine the effect of the most commonly abused drugs (tramadol and morphine), on acetylcholine esterase (AChE), Na+ /K+ -ATPase activities and related parameters, Na+ and K+ as biomarkers of neurotoxicity. Methods: Tramadol - as a weak µ opioid receptor agonist- and morphine - a...

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Bibliographic Details
Main Authors: Abd El-Hamid Mohamed Elwy, Ghada Tabl
Format: Article
Language:English
Published: Electronic Physician 2017-03-01
Series:Electronic Physician
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407239/