Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.

The correlation between personality traits and health outcomes of primary prevention has been examined. However, there is a lack of evidence on the association between the assessment of personality traits and medication adherence for secondary prevention of cardiovascular disease. Thus, this study a...

Full description

Bibliographic Details
Main Authors: Takuji Adachi, Yuki Tsunekawa, Daisuke Tanimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0278534
_version_ 1797954017922383872
author Takuji Adachi
Yuki Tsunekawa
Daisuke Tanimura
author_facet Takuji Adachi
Yuki Tsunekawa
Daisuke Tanimura
author_sort Takuji Adachi
collection DOAJ
description The correlation between personality traits and health outcomes of primary prevention has been examined. However, there is a lack of evidence on the association between the assessment of personality traits and medication adherence for secondary prevention of cardiovascular disease. Thus, this study aimed to explore the association between personality traits and medication adherence, including compliance to prescribed medications and attitudes toward taking medications among patients with cardiovascular disease. This cross-sectional study included patients hospitalized for cardiovascular disease. We assessed the Big Five personality traits (conscientiousness, neuroticism, openness, extraversion, and agreeableness) of each patient at discharge using the Ten-Item Personality Inventory. In addition, we evaluated four aspects of medication adherence using a 12-item version of the medication adherence scale: medication compliance, collaboration with health care providers, willingness to access and use information on medication, and acceptance to take medication. Logistic regression analysis was performed to assess the correlation between the level of each medication adherence domain and each personality trait. The data of 128 patients with cardiovascular disease were analyzed. Higher conscientiousness score was significantly associated with a high compliance score (odds ratio per 1 point increase, 1.90; 95% confidence interval, 1.30-2.79; p = 0.001), high collaboration score (1.90; 1.31-2.76; p = 0.001), and high willingness score (1.74; 1.19-2.54; p = 0.004) after adjustment for potential confounders. Other combinations of personality traits and medication adherence showed no statistically significant correlations in multivariate analyses. The findings of this study suggest that assessment of personality traits, especially conscientiousness, may facilitate patient-medical staff communication for the improvement of medication adherence in patients with cardiovascular disease.
first_indexed 2024-04-10T23:11:09Z
format Article
id doaj.art-666d0d9fdb76482b9e4573a9a51f9362
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-04-10T23:11:09Z
publishDate 2022-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-666d0d9fdb76482b9e4573a9a51f93622023-01-13T05:31:44ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-011712e027853410.1371/journal.pone.0278534Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.Takuji AdachiYuki TsunekawaDaisuke TanimuraThe correlation between personality traits and health outcomes of primary prevention has been examined. However, there is a lack of evidence on the association between the assessment of personality traits and medication adherence for secondary prevention of cardiovascular disease. Thus, this study aimed to explore the association between personality traits and medication adherence, including compliance to prescribed medications and attitudes toward taking medications among patients with cardiovascular disease. This cross-sectional study included patients hospitalized for cardiovascular disease. We assessed the Big Five personality traits (conscientiousness, neuroticism, openness, extraversion, and agreeableness) of each patient at discharge using the Ten-Item Personality Inventory. In addition, we evaluated four aspects of medication adherence using a 12-item version of the medication adherence scale: medication compliance, collaboration with health care providers, willingness to access and use information on medication, and acceptance to take medication. Logistic regression analysis was performed to assess the correlation between the level of each medication adherence domain and each personality trait. The data of 128 patients with cardiovascular disease were analyzed. Higher conscientiousness score was significantly associated with a high compliance score (odds ratio per 1 point increase, 1.90; 95% confidence interval, 1.30-2.79; p = 0.001), high collaboration score (1.90; 1.31-2.76; p = 0.001), and high willingness score (1.74; 1.19-2.54; p = 0.004) after adjustment for potential confounders. Other combinations of personality traits and medication adherence showed no statistically significant correlations in multivariate analyses. The findings of this study suggest that assessment of personality traits, especially conscientiousness, may facilitate patient-medical staff communication for the improvement of medication adherence in patients with cardiovascular disease.https://doi.org/10.1371/journal.pone.0278534
spellingShingle Takuji Adachi
Yuki Tsunekawa
Daisuke Tanimura
Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.
PLoS ONE
title Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.
title_full Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.
title_fullStr Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.
title_full_unstemmed Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.
title_short Association between the Big Five personality traits and medication adherence in patients with cardiovascular disease: A cross-sectional study.
title_sort association between the big five personality traits and medication adherence in patients with cardiovascular disease a cross sectional study
url https://doi.org/10.1371/journal.pone.0278534
work_keys_str_mv AT takujiadachi associationbetweenthebigfivepersonalitytraitsandmedicationadherenceinpatientswithcardiovasculardiseaseacrosssectionalstudy
AT yukitsunekawa associationbetweenthebigfivepersonalitytraitsandmedicationadherenceinpatientswithcardiovasculardiseaseacrosssectionalstudy
AT daisuketanimura associationbetweenthebigfivepersonalitytraitsandmedicationadherenceinpatientswithcardiovasculardiseaseacrosssectionalstudy