Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype
We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-09-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442017301304 |
| _version_ | 1811259357760847872 |
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| author | Pieter D'hulst Jochen Darras Steven Joniau Pieter Mattelaer Linsey Winne Diederik Ponette |
| author_facet | Pieter D'hulst Jochen Darras Steven Joniau Pieter Mattelaer Linsey Winne Diederik Ponette |
| author_sort | Pieter D'hulst |
| collection | DOAJ |
| description | We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis. Microscopic examination showed a Sertoli-only left testis with Leydig-cell hyperplasia and the left epididymis consisted of ovarian tissue with corpora albicantia and maturing follicles. Endocrinological evaluation showed a sex-determining region Y (SRY) negative 46,XX karyotype. We successfully performed a two-stage urethroplasty with buccal mucosa graft to reconstruct his penoscrotal hypospadias. |
| first_indexed | 2024-04-12T18:30:18Z |
| format | Article |
| id | doaj.art-66710627e10f46bbbb45b194eb08af9c |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-04-12T18:30:18Z |
| publishDate | 2017-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-66710627e10f46bbbb45b194eb08af9c2022-12-22T03:21:07ZengElsevierUrology Case Reports2214-44202017-09-0114C454710.1016/j.eucr.2017.06.016Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX KaryotypePieter D'hulst0Jochen Darras1Steven Joniau2Pieter Mattelaer3Linsey Winne4Diederik Ponette5Dept. of Urology Az Damiaan Oostende, Gouwelozestraat 100, 8400 Oostende, BelgiumDept. of Urology Az Damiaan Oostende, Gouwelozestraat 100, 8400 Oostende, BelgiumDept. of Urology UZ Leuven, Herestraat 49, 3000 Leuven, BelgiumDept. of Urology Az Damiaan Oostende, Gouwelozestraat 100, 8400 Oostende, BelgiumDept. of Endocrinology Az Damiaan Oostende, Gouwelozestraat 100, 8400 Oostende, BelgiumDept. of Urology Az Damiaan Oostende, Gouwelozestraat 100, 8400 Oostende, BelgiumWe present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis. Microscopic examination showed a Sertoli-only left testis with Leydig-cell hyperplasia and the left epididymis consisted of ovarian tissue with corpora albicantia and maturing follicles. Endocrinological evaluation showed a sex-determining region Y (SRY) negative 46,XX karyotype. We successfully performed a two-stage urethroplasty with buccal mucosa graft to reconstruct his penoscrotal hypospadias.http://www.sciencedirect.com/science/article/pii/S221444201730130446,XX testicular disorder of sex developmentHypospadiasCryptorchidismUrethroplasty |
| spellingShingle | Pieter D'hulst Jochen Darras Steven Joniau Pieter Mattelaer Linsey Winne Diederik Ponette Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype Urology Case Reports 46,XX testicular disorder of sex development Hypospadias Cryptorchidism Urethroplasty |
| title | Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype |
| title_full | Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype |
| title_fullStr | Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype |
| title_full_unstemmed | Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype |
| title_short | Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype |
| title_sort | two stage urethroplasty with buccal mucosa for penoscrotal hypospadias reconstruction in a male with a 46 xx karyotype |
| topic | 46,XX testicular disorder of sex development Hypospadias Cryptorchidism Urethroplasty |
| url | http://www.sciencedirect.com/science/article/pii/S2214442017301304 |
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