Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study
(1) Background: Ultrasonography is gaining popularity as a diagnostic tool in the study of the oral mucosa. The precision of ultrasound has made it possible to identify the various layers, based on their echogenicity. The aim of this study was to perform a quantitative analysis of healthy oral mucos...
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MDPI AG
2022-07-01
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| Online Access: | https://www.mdpi.com/2076-3417/12/14/6829 |
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| author | Dario Di Stasio Antonio Romano Marco Montella Maria Contaldo Massimo Petruzzi Iquebal Hasan Rosario Serpico Alberta Lucchese |
| author_facet | Dario Di Stasio Antonio Romano Marco Montella Maria Contaldo Massimo Petruzzi Iquebal Hasan Rosario Serpico Alberta Lucchese |
| author_sort | Dario Di Stasio |
| collection | DOAJ |
| description | (1) Background: Ultrasonography is gaining popularity as a diagnostic tool in the study of the oral mucosa. The precision of ultrasound has made it possible to identify the various layers, based on their echogenicity. The aim of this study was to perform a quantitative analysis of healthy oral mucosa based on the analysis of greyscale, echo levels (dB), and attenuation values (dB/cm). (2) Methods: Thirty-three patients (17 females and 16 males; 58.42 ± 13.29 y.o) were recruited for this study. The images were acquired with the GE Logiq-e R7 with a linear probe at 18 MHz frequency (harmonic). For each tissue (epithelium, rete ridges, connective tissue, muscle, and bone), regions of interest were traced for the analysis of echo levels, grey levels, and attenuation values. One-way ANOVA and pairwise comparison were performed. (3) Results: Three-hundred and thirty images were analyzed. Analysis of echo levels and grey levels showed a significant difference between epithelium and rete ridges (<i>p</i> = 0.001), and between rete ridges and connective tissue (<i>p</i> = 0.001), but not between epithelium and connective tissue (<i>p</i> = 0.831) or connective and muscle layers (<i>p</i> = 0.383). The attenuation values appeared to be specific for each tissue layer (<i>p</i> = 0.001). (4) Conclusions: Quantitative analysis applied to ultrasound imaging of the oral mucosa allows the definition of specific tissue areas. |
| first_indexed | 2024-03-09T03:45:22Z |
| format | Article |
| id | doaj.art-6671426b5b244dd1b034824a52dd5c0b |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T03:45:22Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-6671426b5b244dd1b034824a52dd5c0b2023-12-03T14:34:39ZengMDPI AGApplied Sciences2076-34172022-07-011214682910.3390/app12146829Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional StudyDario Di Stasio0Antonio Romano1Marco Montella2Maria Contaldo3Massimo Petruzzi4Iquebal Hasan5Rosario Serpico6Alberta Lucchese7Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyDepartment of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyInterdisciplinary Department of Medicine, University of Bari, 70121 Bari, ItalyUNC Adams School of Dentistry, 385 S Columbia St., Chapel Hill, NC 27599, USAMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, ItalyMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy(1) Background: Ultrasonography is gaining popularity as a diagnostic tool in the study of the oral mucosa. The precision of ultrasound has made it possible to identify the various layers, based on their echogenicity. The aim of this study was to perform a quantitative analysis of healthy oral mucosa based on the analysis of greyscale, echo levels (dB), and attenuation values (dB/cm). (2) Methods: Thirty-three patients (17 females and 16 males; 58.42 ± 13.29 y.o) were recruited for this study. The images were acquired with the GE Logiq-e R7 with a linear probe at 18 MHz frequency (harmonic). For each tissue (epithelium, rete ridges, connective tissue, muscle, and bone), regions of interest were traced for the analysis of echo levels, grey levels, and attenuation values. One-way ANOVA and pairwise comparison were performed. (3) Results: Three-hundred and thirty images were analyzed. Analysis of echo levels and grey levels showed a significant difference between epithelium and rete ridges (<i>p</i> = 0.001), and between rete ridges and connective tissue (<i>p</i> = 0.001), but not between epithelium and connective tissue (<i>p</i> = 0.831) or connective and muscle layers (<i>p</i> = 0.383). The attenuation values appeared to be specific for each tissue layer (<i>p</i> = 0.001). (4) Conclusions: Quantitative analysis applied to ultrasound imaging of the oral mucosa allows the definition of specific tissue areas.https://www.mdpi.com/2076-3417/12/14/6829ultrasound imagingoral mucosaquantitative analysis |
| spellingShingle | Dario Di Stasio Antonio Romano Marco Montella Maria Contaldo Massimo Petruzzi Iquebal Hasan Rosario Serpico Alberta Lucchese Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study Applied Sciences ultrasound imaging oral mucosa quantitative analysis |
| title | Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study |
| title_full | Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study |
| title_fullStr | Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study |
| title_full_unstemmed | Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study |
| title_short | Quantitative Ultrasound Analysis of Oral Mucosa: An Observational Cross-Sectional Study |
| title_sort | quantitative ultrasound analysis of oral mucosa an observational cross sectional study |
| topic | ultrasound imaging oral mucosa quantitative analysis |
| url | https://www.mdpi.com/2076-3417/12/14/6829 |
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