Domain-PFP allows protein function prediction using function-aware domain embedding representations

Abstract Domains are functional and structural units of proteins that govern various biological functions performed by the proteins. Therefore, the characterization of domains in a protein can serve as a proper functional representation of proteins. Here, we employ a self-supervised protocol to deri...

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Bibliographic Details
Main Authors: Nabil Ibtehaz, Yuki Kagaya, Daisuke Kihara
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05476-9