A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em>
Fusarium wilt of flax is an aggressive disease caused by the soil-borne fungal pathogen <i>Fusarium oxysporum</i> f. sp. <i>lini</i>. It is a challenging pathogen presenting a constant threat to flax production industry worldwide. Previously, we reported chromosome-level asse...
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MDPI AG
2021-03-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/22/5/2665 |
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| author | Anastasia Samsonova Alexander Kanapin Michael Bankin Anton Logachev Maria Gretsova Tatyana Rozhmina Maria Samsonova |
| author_facet | Anastasia Samsonova Alexander Kanapin Michael Bankin Anton Logachev Maria Gretsova Tatyana Rozhmina Maria Samsonova |
| author_sort | Anastasia Samsonova |
| collection | DOAJ |
| description | Fusarium wilt of flax is an aggressive disease caused by the soil-borne fungal pathogen <i>Fusarium oxysporum</i> f. sp. <i>lini</i>. It is a challenging pathogen presenting a constant threat to flax production industry worldwide. Previously, we reported chromosome-level assemblies of 5 highly pathogenic <i>F. oxysporum</i> f. sp. <i>lini</i> strains. We sought to characterize the genomic architecture of the fungus and outline evolutionary mechanisms shaping the pathogen genome. Here, we reveal the complex multi-compartmentalized genome organization and uncover its diverse evolutionary dynamics, which boosts genetic diversity and facilitates host adaptation. In addition, our results suggest that host of functions implicated in the life cycle of mobile genetic elements are main contributors to dissimilarity between proteomes of different <i>Fusaria</i>. Finally, our experiments demonstrate that mobile genetics elements are expressed in planta upon infection, alluding to their role in pathogenicity. On the whole, these results pave the way for further in-depth studies of evolutionary forces shaping the host–pathogen interaction. |
| first_indexed | 2024-03-09T05:10:03Z |
| format | Article |
| id | doaj.art-6679eb05a52c4aaba21b7449d52995ed |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T05:10:03Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-6679eb05a52c4aaba21b7449d52995ed2023-12-03T12:50:00ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-03-01225266510.3390/ijms22052665A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em>Anastasia Samsonova0Alexander Kanapin1Michael Bankin2Anton Logachev3Maria Gretsova4Tatyana Rozhmina5Maria Samsonova6Institute of Translational Biomedicine, Saint Petersburg State University, 199034 Saint Petersburg, RussiaMathematical Biology & Bioinformatics Laboratory, Peter the Great Saint Petersburg Polytechnic University, 195251 St. Petersburg, RussiaMathematical Biology & Bioinformatics Laboratory, Peter the Great Saint Petersburg Polytechnic University, 195251 St. Petersburg, RussiaMathematical Biology & Bioinformatics Laboratory, Peter the Great Saint Petersburg Polytechnic University, 195251 St. Petersburg, RussiaInstitute of Translational Biomedicine, Saint Petersburg State University, 199034 Saint Petersburg, RussiaLaboratory of Breeding Technologies, Federal Research Center for Bast Fiber Crops, 172002 Torzhok, RussiaMathematical Biology & Bioinformatics Laboratory, Peter the Great Saint Petersburg Polytechnic University, 195251 St. Petersburg, RussiaFusarium wilt of flax is an aggressive disease caused by the soil-borne fungal pathogen <i>Fusarium oxysporum</i> f. sp. <i>lini</i>. It is a challenging pathogen presenting a constant threat to flax production industry worldwide. Previously, we reported chromosome-level assemblies of 5 highly pathogenic <i>F. oxysporum</i> f. sp. <i>lini</i> strains. We sought to characterize the genomic architecture of the fungus and outline evolutionary mechanisms shaping the pathogen genome. Here, we reveal the complex multi-compartmentalized genome organization and uncover its diverse evolutionary dynamics, which boosts genetic diversity and facilitates host adaptation. In addition, our results suggest that host of functions implicated in the life cycle of mobile genetic elements are main contributors to dissimilarity between proteomes of different <i>Fusaria</i>. Finally, our experiments demonstrate that mobile genetics elements are expressed in planta upon infection, alluding to their role in pathogenicity. On the whole, these results pave the way for further in-depth studies of evolutionary forces shaping the host–pathogen interaction.https://www.mdpi.com/1422-0067/22/5/2665<i>Fusarium oxysporum</i> f. sp. <i>lini</i>flaxgenome architecturegenome evolutiontransposable elementscomparative genomics |
| spellingShingle | Anastasia Samsonova Alexander Kanapin Michael Bankin Anton Logachev Maria Gretsova Tatyana Rozhmina Maria Samsonova A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em> International Journal of Molecular Sciences <i>Fusarium oxysporum</i> f. sp. <i>lini</i> flax genome architecture genome evolution transposable elements comparative genomics |
| title | A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em> |
| title_full | A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em> |
| title_fullStr | A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em> |
| title_full_unstemmed | A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em> |
| title_short | A Genomic Blueprint of Flax Fungal Parasite <em>Fusarium oxysporum</em> f. sp. <em>lini</em> |
| title_sort | genomic blueprint of flax fungal parasite em fusarium oxysporum em f sp em lini em |
| topic | <i>Fusarium oxysporum</i> f. sp. <i>lini</i> flax genome architecture genome evolution transposable elements comparative genomics |
| url | https://www.mdpi.com/1422-0067/22/5/2665 |
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