In Vitro/In Vivo Preparation and Evaluation of cRGDyK Peptide-Modified Polydopamine-Bridged Paclitaxel-Loaded Nanoparticles

In Vitro/In Vivo Preparation and Evaluation of cRGDyK Peptide-Modified Polydopamine-Bridged Paclitaxel-Loaded Nanoparticles

Cancer remains a disease with one of the highest mortality rates worldwide. The poor water solubility and tissue selectivity of commonly used chemotherapeutic agents contribute to their poor efficacy and serious adverse effects. This study proposes an alternative to the traditional physicochemically...

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Bibliographic Details
Main Authors: Dan Yun, Dengyuan Liu, Jinlin Liu, Yanyi Feng, Hongyu Chen, Simiao Chen, Qingchun Xie
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
nanoparticles
RGD
PLGA
surface modification
antitumor effect
Online Access:https://www.mdpi.com/1999-4923/15/11/2644

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