Human metapneumovirus in Southern Brazil
Abstract INTRODUCTION Infections caused by respiratory viruses are important problems worldwide, especially in children. Human metapneumovirus (hMPV) is a respiratory pathogen and causes severe infections with nonspecific symptoms. This study reports the hMPV occurrence and dissemination in southe...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000100030&lng=en&tlng=en |
| _version_ | 1811246039985815552 |
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| author | Tatiana Schäffer Gregianini Claudete Farina Seadi Ivone Menegolla Letícia Garay Martins Nilo Ikuta Jonas Michel Wolf Vagner Ricardo Lunge |
| author_facet | Tatiana Schäffer Gregianini Claudete Farina Seadi Ivone Menegolla Letícia Garay Martins Nilo Ikuta Jonas Michel Wolf Vagner Ricardo Lunge |
| author_sort | Tatiana Schäffer Gregianini |
| collection | DOAJ |
| description | Abstract INTRODUCTION Infections caused by respiratory viruses are important problems worldwide, especially in children. Human metapneumovirus (hMPV) is a respiratory pathogen and causes severe infections with nonspecific symptoms. This study reports the hMPV occurrence and dissemination in southern Brazil and compares the frequency of occurrence of this virus and the human respiratory syncytial virus (hRSV) in the epidemiological weeks in a three-year period (2009-2011). METHODS: In total, 545 nasopharyngeal (NP) specimens from individuals with Severe Acute Respiratory Syndrome (SARS) who were negative for other seven respiratory viruses were analyzed for the presence of hMPV. Human metapneumovirus was detected by direct immunofluorescence and real-time reverse transcription polymerase chain reaction. RESULTS: hMPV was detected in 109 patients from the main geographic regions of the southernmost state of Brazil, presenting similar overall prevalence in males (46.8%) and females (53.2%). Among children who were less than six years old, hMPV was detected in 99 samples of all age groups, with a higher frequency in infants who were less than one year old (45.7%) compared to all other age groups until six years. hMPV and hRSV infection occurred in almost the same epidemiological weeks (EWs) of each year, with peaks of incidence between EW 31/37 and EW 26/38 for the years 2009 and 2011, respectively. hMPV was further detected in several cases of SARS and it was the only virus detected in three deaths. CONCLUSIONS These findings indicate that hMPV is in circulation in southern Brazil and highlight the importance of diagnosing hMPV for influenza-like illness in the population. |
| first_indexed | 2024-04-12T14:47:55Z |
| format | Article |
| id | doaj.art-667a441fa6474b8082ffa07584bc6075 |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:47:55Z |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-667a441fa6474b8082ffa07584bc60752022-12-22T03:28:34ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-9849511303810.1590/0037-8682-0435-2017S0037-86822018000100030Human metapneumovirus in Southern BrazilTatiana Schäffer GregianiniClaudete Farina SeadiIvone MenegollaLetícia Garay MartinsNilo IkutaJonas Michel WolfVagner Ricardo LungeAbstract INTRODUCTION Infections caused by respiratory viruses are important problems worldwide, especially in children. Human metapneumovirus (hMPV) is a respiratory pathogen and causes severe infections with nonspecific symptoms. This study reports the hMPV occurrence and dissemination in southern Brazil and compares the frequency of occurrence of this virus and the human respiratory syncytial virus (hRSV) in the epidemiological weeks in a three-year period (2009-2011). METHODS: In total, 545 nasopharyngeal (NP) specimens from individuals with Severe Acute Respiratory Syndrome (SARS) who were negative for other seven respiratory viruses were analyzed for the presence of hMPV. Human metapneumovirus was detected by direct immunofluorescence and real-time reverse transcription polymerase chain reaction. RESULTS: hMPV was detected in 109 patients from the main geographic regions of the southernmost state of Brazil, presenting similar overall prevalence in males (46.8%) and females (53.2%). Among children who were less than six years old, hMPV was detected in 99 samples of all age groups, with a higher frequency in infants who were less than one year old (45.7%) compared to all other age groups until six years. hMPV and hRSV infection occurred in almost the same epidemiological weeks (EWs) of each year, with peaks of incidence between EW 31/37 and EW 26/38 for the years 2009 and 2011, respectively. hMPV was further detected in several cases of SARS and it was the only virus detected in three deaths. CONCLUSIONS These findings indicate that hMPV is in circulation in southern Brazil and highlight the importance of diagnosing hMPV for influenza-like illness in the population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000100030&lng=en&tlng=enHuman metapneumovirusHuman respiratory syncytial virusEpidemiologyRespiratory viruses |
| spellingShingle | Tatiana Schäffer Gregianini Claudete Farina Seadi Ivone Menegolla Letícia Garay Martins Nilo Ikuta Jonas Michel Wolf Vagner Ricardo Lunge Human metapneumovirus in Southern Brazil Revista da Sociedade Brasileira de Medicina Tropical Human metapneumovirus Human respiratory syncytial virus Epidemiology Respiratory viruses |
| title | Human metapneumovirus in Southern Brazil |
| title_full | Human metapneumovirus in Southern Brazil |
| title_fullStr | Human metapneumovirus in Southern Brazil |
| title_full_unstemmed | Human metapneumovirus in Southern Brazil |
| title_short | Human metapneumovirus in Southern Brazil |
| title_sort | human metapneumovirus in southern brazil |
| topic | Human metapneumovirus Human respiratory syncytial virus Epidemiology Respiratory viruses |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000100030&lng=en&tlng=en |
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