Infant age inversely correlates with gut carriage of resistance genes, reflecting modifications in microbial carbohydrate metabolism during early life

Infant age inversely correlates with gut carriage of resistance genes, reflecting modifications in microbial carbohydrate metabolism during early life

Abstract The infant gut microbiome is increasingly recognized as a reservoir of antibiotic resistance genes, yet the assembly of gut resistome in infants and its influencing factors remain largely unknown. We characterized resistome in 4132 metagenomes from 963 infants in six countries and 4285 resi...

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Bibliographic Details
Main Authors: Xinming Xu, Qingying Feng, Tao Zhang, Yunlong Gao, Qu Cheng, Wanqiu Zhang, Qinglong Wu, Ke Xu, Yucan Li, Nhu Nguyen, Diana H. Taft, David A. Mills, Danielle G. Lemay, Weiyun Zhu, Shengyong Mao, Anyun Zhang, Kelin Xu, Jinxin Liu
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:iMeta
Subjects:
age
antimicrobial resistance genes
carbohydrate metabolism
diet
infant gut resistome
metagenomics
Online Access:https://doi.org/10.1002/imt2.169

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