Facile Chemical Access to Biologically Active Norcantharidin Derivatives from Biomass

Facile Chemical Access to Biologically Active Norcantharidin Derivatives from Biomass

Reductive amination of 2,5-diformylfuran (DFF) was used to implement the transition from bio-derived 5-hydroxymethylfurfural (HMF) to pharmaceuticals. The synthesized bis(aminomethyl)furans were utilized as building blocks for the construction of new derivatives with structural cores of naturally oc...

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Bibliographic Details
Main Authors: Konstantin I. Galkin, Fedor A. Kucherov, Oleg N. Markov, Ksenia S. Egorova, Alexandra V. Posvyatenko, Valentine P. Ananikov
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
biomass
2,5-diformylfuran
reductive amination
norcantharidin
diastereoselectivity
Diels–Alder reaction
Online Access:https://www.mdpi.com/1420-3049/22/12/2210

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