Lactulose vs Lactuloseand inulin in treatment of pediatric constipation
Background: Assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Objective: To assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Patients and Methods: One hundred forty...
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| Format: | Article |
| Language: | English |
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College of medicine/ University of Diyala
2023-04-01
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| Series: | Diyala Journal of Medicine |
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| Online Access: | https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/975 |
| _version_ | 1827632569941753856 |
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| author | Salar Sabah Berdawd, Sasan Loqa Hanna, Yasir Kakameen Hamad |
| author_facet | Salar Sabah Berdawd, Sasan Loqa Hanna, Yasir Kakameen Hamad |
| author_sort | Salar Sabah Berdawd, |
| collection | DOAJ |
| description |
Background: Assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group.
Objective: To assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group.
Patients and Methods: One hundred forty-six patients with fuctionalconstipation were chosen in a non-randomized superiority trial manner as they were convenient to enroll due to their presentation to the outpatient clinic during the period from August 2019 to February 2022.Patient received either a solution of lactulose 3.3g/5ml in group A or a solution of 4.005g Inulin fiber and 4.005g lactulose per 20ml in group B.
Results: Total of 146 children were included; all, 146 patients completed the study. In the lactulose group, 19 patients were on therapy for less than 6 months, and 48 were on therapy for more than 6 months. In the lactulose + fiber group, 59 patients were on therapy for less than 6 months, and 20 were on therapy for more than 6 months. No serious adverse effects were registered but 18 (27%) of children in the lactulose group encountered side effects, while 11 (14%) of children in the lactulose + fiber group encountered side effects.
Conclusion: A solution of Lactulose + fiber is superior to a solution of Lactulose alone in terms of efficacy for the treatment of constipation in the pediatric age group. It also has a lower side effects profile.
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| first_indexed | 2024-03-09T14:47:24Z |
| format | Article |
| id | doaj.art-6680db5e3d10481bb316c44115b6da81 |
| institution | Directory Open Access Journal |
| issn | 2219-9764 2617-8982 |
| language | English |
| last_indexed | 2024-03-09T14:47:24Z |
| publishDate | 2023-04-01 |
| publisher | College of medicine/ University of Diyala |
| record_format | Article |
| series | Diyala Journal of Medicine |
| spelling | doaj.art-6680db5e3d10481bb316c44115b6da812023-11-26T23:22:39ZengCollege of medicine/ University of DiyalaDiyala Journal of Medicine2219-97642617-89822023-04-0124110.26505/djm.v24i1.975Lactulose vs Lactuloseand inulin in treatment of pediatric constipationSalar Sabah Berdawd,Sasan Loqa Hanna,Yasir Kakameen Hamad Background: Assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Objective: To assess the efficacy of combining fiber and lactulose in the treatment of constipation in the pediatric age group. Patients and Methods: One hundred forty-six patients with fuctionalconstipation were chosen in a non-randomized superiority trial manner as they were convenient to enroll due to their presentation to the outpatient clinic during the period from August 2019 to February 2022.Patient received either a solution of lactulose 3.3g/5ml in group A or a solution of 4.005g Inulin fiber and 4.005g lactulose per 20ml in group B. Results: Total of 146 children were included; all, 146 patients completed the study. In the lactulose group, 19 patients were on therapy for less than 6 months, and 48 were on therapy for more than 6 months. In the lactulose + fiber group, 59 patients were on therapy for less than 6 months, and 20 were on therapy for more than 6 months. No serious adverse effects were registered but 18 (27%) of children in the lactulose group encountered side effects, while 11 (14%) of children in the lactulose + fiber group encountered side effects. Conclusion: A solution of Lactulose + fiber is superior to a solution of Lactulose alone in terms of efficacy for the treatment of constipation in the pediatric age group. It also has a lower side effects profile. https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/975Abdominal pain, bloating, constipation, distension, lactulose, inulin |
| spellingShingle | Salar Sabah Berdawd, Sasan Loqa Hanna, Yasir Kakameen Hamad Lactulose vs Lactuloseand inulin in treatment of pediatric constipation Diyala Journal of Medicine Abdominal pain, bloating, constipation, distension, lactulose, inulin |
| title | Lactulose vs Lactuloseand inulin in treatment of pediatric constipation |
| title_full | Lactulose vs Lactuloseand inulin in treatment of pediatric constipation |
| title_fullStr | Lactulose vs Lactuloseand inulin in treatment of pediatric constipation |
| title_full_unstemmed | Lactulose vs Lactuloseand inulin in treatment of pediatric constipation |
| title_short | Lactulose vs Lactuloseand inulin in treatment of pediatric constipation |
| title_sort | lactulose vs lactuloseand inulin in treatment of pediatric constipation |
| topic | Abdominal pain, bloating, constipation, distension, lactulose, inulin |
| url | https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/975 |
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