Predicting metabolic adaptation from networks of mutational paths

The structure and dynamics of microbial communities reflect trade-offs in the ability to use different resources. Here, Josephides and Swain incorporate metabolic trade-offs into an eco-evolutionary model to predict networks of mutational paths and the evolutionary outcomes for microbial communities...

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Main Authors: Christos Josephides, Peter S. Swain
Format: Article
Language:English
Published: Nature Portfolio 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00828-6
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author Christos Josephides
Peter S. Swain
author_facet Christos Josephides
Peter S. Swain
author_sort Christos Josephides
collection DOAJ
description The structure and dynamics of microbial communities reflect trade-offs in the ability to use different resources. Here, Josephides and Swain incorporate metabolic trade-offs into an eco-evolutionary model to predict networks of mutational paths and the evolutionary outcomes for microbial communities.
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spelling doaj.art-6686588b28974b0aad6131eb5b8c4a102022-12-21T22:56:44ZengNature PortfolioNature Communications2041-17232017-09-018111510.1038/s41467-017-00828-6Predicting metabolic adaptation from networks of mutational pathsChristos Josephides0Peter S. Swain1SynthSys—Synthetic and Systems Biology, School of Biological Sciences, University of EdinburghSynthSys—Synthetic and Systems Biology, School of Biological Sciences, University of EdinburghThe structure and dynamics of microbial communities reflect trade-offs in the ability to use different resources. Here, Josephides and Swain incorporate metabolic trade-offs into an eco-evolutionary model to predict networks of mutational paths and the evolutionary outcomes for microbial communities.https://doi.org/10.1038/s41467-017-00828-6
spellingShingle Christos Josephides
Peter S. Swain
Predicting metabolic adaptation from networks of mutational paths
Nature Communications
title Predicting metabolic adaptation from networks of mutational paths
title_full Predicting metabolic adaptation from networks of mutational paths
title_fullStr Predicting metabolic adaptation from networks of mutational paths
title_full_unstemmed Predicting metabolic adaptation from networks of mutational paths
title_short Predicting metabolic adaptation from networks of mutational paths
title_sort predicting metabolic adaptation from networks of mutational paths
url https://doi.org/10.1038/s41467-017-00828-6
work_keys_str_mv AT christosjosephides predictingmetabolicadaptationfromnetworksofmutationalpaths
AT petersswain predictingmetabolicadaptationfromnetworksofmutationalpaths