Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy
Objective: The botulinum neurotoxin type A (BoNT-A) intramuscular injection is a safe and reliable method to treat increased spasticity in spastic cerebral palsy (CP). Although BNT-A injections may be administered under local anesthesia, many clinicians prefer injections under general anesthesia in...
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| Format: | Article |
| Language: | English |
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Sakarya University
2022-03-01
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| Series: | Sakarya Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/2128827 |
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| author | Muharrem Inan Ozlem Kaya Elif Diler Ermeç Feryal Biçer Türkmenoğlu İlker Abdullah Sarıkaya Sema Ertan Birsel Ozan Ali Erdal Baris Gorgun |
| author_facet | Muharrem Inan Ozlem Kaya Elif Diler Ermeç Feryal Biçer Türkmenoğlu İlker Abdullah Sarıkaya Sema Ertan Birsel Ozan Ali Erdal Baris Gorgun |
| author_sort | Muharrem Inan |
| collection | DOAJ |
| description | Objective: The botulinum neurotoxin type A (BoNT-A) intramuscular injection is a safe and reliable method to treat increased spasticity in spastic cerebral palsy (CP). Although BNT-A injections may be administered under local anesthesia, many clinicians prefer injections under general anesthesia in the operating room, especially for children. The purpose of the present study was to evaluate the safety and efficacy of administering BNT-A injections to children with spastic CP under sevoflurane mask anesthesia.
Materials and Methods: Files of 61 children with CP who received 191 BoNT-A injections under sevoflurane mask anesthesia were analyzed retrospectively. The time from the beginning of anesthesia to the end of the procedure was recorded. The BNT-A dose per muscle was 3–6 IU/kg body weight for lower extremity muscles and 1–3 IU/kg body weight for upper extremity muscles.
Results: The mean age of the children was 42 months. The mean procedure time was 15 min. There were no complications related to anesthesia or the BTN-A injection procedure.
Conclusion: BTN-A injections in children with spastic CP may be safely and effectively administered under sevoflurane mask anesthesia without any procedural or anesthetic complications. |
| first_indexed | 2024-03-08T12:44:23Z |
| format | Article |
| id | doaj.art-668b049f9fe8458180adc9bb1acd7e5d |
| institution | Directory Open Access Journal |
| issn | 2146-409X |
| language | English |
| last_indexed | 2024-03-08T12:44:23Z |
| publishDate | 2022-03-01 |
| publisher | Sakarya University |
| record_format | Article |
| series | Sakarya Tıp Dergisi |
| spelling | doaj.art-668b049f9fe8458180adc9bb1acd7e5d2024-01-21T07:40:09ZengSakarya UniversitySakarya Tıp Dergisi2146-409X2022-03-01121586210.31832/smj.103577328Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral PalsyMuharrem Inan0Ozlem Kaya1Elif Diler Ermeç2Feryal Biçer Türkmenoğlu3İlker Abdullah Sarıkaya4Sema Ertan Birsel5Ozan Ali Erdal6Baris Gorgun7Ortopediatri Istanbul, Academy of Pediatric OrthopaedicsNisantasi Hospital, Anesthesiology and ReanimationHisar Intercontinental Hospital, Anesthesiology and ReanimationIstanbul Cerrahi Hospital, Anesthesiology and ReanimationOrtopediatri Istanbul, Academy of Pediatric OrthopaedicsTurkish Ministry of Health, Basaksehir Cam and Sakura City Hospital, Orthopaedics and Traumatology, Istanbul, TURKEYOrtopediatri Istanbul, Academy of Pediatric OrthopaedicsOrtopediatri İstanbul, Academy of Pediatric OrthopaedicsObjective: The botulinum neurotoxin type A (BoNT-A) intramuscular injection is a safe and reliable method to treat increased spasticity in spastic cerebral palsy (CP). Although BNT-A injections may be administered under local anesthesia, many clinicians prefer injections under general anesthesia in the operating room, especially for children. The purpose of the present study was to evaluate the safety and efficacy of administering BNT-A injections to children with spastic CP under sevoflurane mask anesthesia. Materials and Methods: Files of 61 children with CP who received 191 BoNT-A injections under sevoflurane mask anesthesia were analyzed retrospectively. The time from the beginning of anesthesia to the end of the procedure was recorded. The BNT-A dose per muscle was 3–6 IU/kg body weight for lower extremity muscles and 1–3 IU/kg body weight for upper extremity muscles. Results: The mean age of the children was 42 months. The mean procedure time was 15 min. There were no complications related to anesthesia or the BTN-A injection procedure. Conclusion: BTN-A injections in children with spastic CP may be safely and effectively administered under sevoflurane mask anesthesia without any procedural or anesthetic complications.https://dergipark.org.tr/tr/download/article-file/2128827botulinum toxincerebral palsyinhalation anesthesiasevofluranebotulinum toksinserebral palsiinhalasyon anestezisisevofluran |
| spellingShingle | Muharrem Inan Ozlem Kaya Elif Diler Ermeç Feryal Biçer Türkmenoğlu İlker Abdullah Sarıkaya Sema Ertan Birsel Ozan Ali Erdal Baris Gorgun Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy Sakarya Tıp Dergisi botulinum toxin cerebral palsy inhalation anesthesia sevoflurane botulinum toksin serebral palsi inhalasyon anestezisi sevofluran |
| title | Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy |
| title_full | Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy |
| title_fullStr | Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy |
| title_full_unstemmed | Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy |
| title_short | Clinical Results of Sevoflurane Inhalation Anesthesia for Botulinum Neurotoxin Treatment in Children with Cerebral Palsy |
| title_sort | clinical results of sevoflurane inhalation anesthesia for botulinum neurotoxin treatment in children with cerebral palsy |
| topic | botulinum toxin cerebral palsy inhalation anesthesia sevoflurane botulinum toksin serebral palsi inhalasyon anestezisi sevofluran |
| url | https://dergipark.org.tr/tr/download/article-file/2128827 |
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