Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants
Abortion is one of the leading causes of economic losses in the livestock industry worldwide. Chlamydia abortus, Coxiella burnetii, and Brucella spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district J...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-07-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2023.1195274/full |
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| author | Muhammad Abid Zeeshan Sarmad Ali Ishtiaq Ahmed Aziz ur Rehman Muhammad Kamran Rafique Amar Nasir Aman Ullah Khan Muhammad Kashif Katja Mertens-Scholz Muhammad Imran Arshad Syed Ehtisham-ul-Haque Heinrich Neubauer |
| author_facet | Muhammad Abid Zeeshan Sarmad Ali Ishtiaq Ahmed Aziz ur Rehman Muhammad Kamran Rafique Amar Nasir Aman Ullah Khan Muhammad Kashif Katja Mertens-Scholz Muhammad Imran Arshad Syed Ehtisham-ul-Haque Heinrich Neubauer |
| author_sort | Muhammad Abid Zeeshan |
| collection | DOAJ |
| description | Abortion is one of the leading causes of economic losses in the livestock industry worldwide. Chlamydia abortus, Coxiella burnetii, and Brucella spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district Jhang. A total of 385 serum samples were taken from the sheep and goats from different flocks with a history of abortion and subjected to i-ELISA. Further, samples were analysed for liver enzymes and total serum protein using a semi-automated chemistry analyzer. The result of indirect commercial ELISA showed 13.0, 4.2 and 11.2% prevalence for Coxiella burnetii, Chlamydia abortus, and Brucella spp., respectively. Values of different serum parameters (ALT, AST, and total protein) of seropositive animals were also determined. There was a significant rise in AST and ALT values of infected animals (p ≤ 0.05). Total protein decreased for all three infections, but a significant drop was noted in Brucella positive sheep serum samples. Various risk factors were studied. Binary logistic regression proved a significant role of ticks for coxiellosis and brucellosis. Age, parity, and species did not impact the prevalence of diseases studied. |
| first_indexed | 2024-03-12T00:43:11Z |
| format | Article |
| id | doaj.art-668e1b476efd4cb6ad17f96292ab27b8 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-03-12T00:43:11Z |
| publishDate | 2023-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-668e1b476efd4cb6ad17f96292ab27b82023-09-15T01:50:01ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692023-07-011010.3389/fvets.2023.11952741195274Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminantsMuhammad Abid Zeeshan0Sarmad Ali1Ishtiaq Ahmed2Aziz ur Rehman3Muhammad Kamran Rafique4Amar Nasir5Aman Ullah Khan6Muhammad Kashif7Katja Mertens-Scholz8Muhammad Imran Arshad9Syed Ehtisham-ul-Haque10Heinrich Neubauer11Department of Pathobiology (Pathology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Pathobiology (Pathology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Pathobiology (Pathology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Pathobiology (Pathology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Pathobiology (Pathology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Clinical Sciences, University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Pathobiology (Microbiology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanDepartment of Clinical Sciences, University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanInstitute of Bacterial Infections and Zoonoses, Friedrich-Loeffler-Institut, Jena, GermanyInstitute of Microbiology, University of Agriculture, Faisalabad, PakistanDepartment of Pathobiology (Microbiology Section), University of Veterinary and Animal Sciences Lahore (Sub-Campus Jhang), Jhang, PakistanInstitute of Bacterial Infections and Zoonoses, Friedrich-Loeffler-Institut, Jena, GermanyAbortion is one of the leading causes of economic losses in the livestock industry worldwide. Chlamydia abortus, Coxiella burnetii, and Brucella spp. are the leading cause of late fetal loss in small ruminants. This study determined the seroprevalence of these agents in small ruminants in district Jhang. A total of 385 serum samples were taken from the sheep and goats from different flocks with a history of abortion and subjected to i-ELISA. Further, samples were analysed for liver enzymes and total serum protein using a semi-automated chemistry analyzer. The result of indirect commercial ELISA showed 13.0, 4.2 and 11.2% prevalence for Coxiella burnetii, Chlamydia abortus, and Brucella spp., respectively. Values of different serum parameters (ALT, AST, and total protein) of seropositive animals were also determined. There was a significant rise in AST and ALT values of infected animals (p ≤ 0.05). Total protein decreased for all three infections, but a significant drop was noted in Brucella positive sheep serum samples. Various risk factors were studied. Binary logistic regression proved a significant role of ticks for coxiellosis and brucellosis. Age, parity, and species did not impact the prevalence of diseases studied.https://www.frontiersin.org/articles/10.3389/fvets.2023.1195274/fullabortionBrucellaCoxiellaChlamydiasmall ruminants |
| spellingShingle | Muhammad Abid Zeeshan Sarmad Ali Ishtiaq Ahmed Aziz ur Rehman Muhammad Kamran Rafique Amar Nasir Aman Ullah Khan Muhammad Kashif Katja Mertens-Scholz Muhammad Imran Arshad Syed Ehtisham-ul-Haque Heinrich Neubauer Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants Frontiers in Veterinary Science abortion Brucella Coxiella Chlamydia small ruminants |
| title | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
| title_full | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
| title_fullStr | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
| title_full_unstemmed | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
| title_short | Sero-epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
| title_sort | sero epidemiological study of zoonotic bacterial abortifacient agents in small ruminants |
| topic | abortion Brucella Coxiella Chlamydia small ruminants |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2023.1195274/full |
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