Complement factor B in high glucose–induced podocyte injury and diabetic kidney disease

Complement factor B in high glucose–induced podocyte injury and diabetic kidney disease

The role and mechanisms for upregulating complement factor B (CFB) expression in podocyte dysfunction in diabetic kidney disease (DKD) are not fully understood. Here, analyzing Gene Expression Omnibus GSE30528 data, we identified genes enriched in mTORC1 signaling, CFB, and complement alternative pa...

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Bibliographic Details
Main Authors: Qingmiao Lu, Qing Hou, Kai Cao, Xiaoli Sun, Yan Liang, Mengru Gu, Xian Xue, Allan Zijian Zhao, Chunsun Dai
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-10-01
Series:JCI Insight
Subjects:
Inflammation
Nephrology
Online Access:https://doi.org/10.1172/jci.insight.147716

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