Vision-related quality of life in first stroke patients with homonymous visual field defects
<p>Abstract</p> <p>Background</p> <p>To evaluate vision-related and health-related quality of life (VRQoL, HRQoL) in first stroke patients with homonymous visual field defects (VFD) with respect to the extent of the lesion. Since VFD occur in approximately 10% of stroke...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-03-01
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| Series: | Health and Quality of Life Outcomes |
| Online Access: | http://www.hqlo.com/content/8/1/33 |
| _version_ | 1828238809181978624 |
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| author | Sabel Bernhard A Franke Gabriele H Gall Carolin |
| author_facet | Sabel Bernhard A Franke Gabriele H Gall Carolin |
| author_sort | Sabel Bernhard A |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To evaluate vision-related and health-related quality of life (VRQoL, HRQoL) in first stroke patients with homonymous visual field defects (VFD) with respect to the extent of the lesion. Since VFD occur in approximately 10% of stroke patients the main purpose of the study was to investigate the additional impact of VFD in stroke patients hypothesizing that VFD causes diminished VRQoL.</p> <p>Methods</p> <p>In 177 first stroke patients with persisting VFD 2.5 years after posterior-parietal lesions VRQoL was assessed by the National-Eye-Institute-Visual-Functioning-Questionnaire (NEI-VFQ) and HRQoL by the Medical-Outcome-Study Short-Form-36 Health-Survey (SF-36). Questionnaire results of VFD-patients were compared with age- and sex-matched healthy controls and with general non-selected stroke samples as published elsewhere. VFD-type and visual acuity were partially correlated with questionnaire results.</p> <p>Results</p> <p>Compared to healthy controls VFD-patients had lower NEI-VFQ scores except ocular pain (Z-range -11.34 to -3.35) and lower SF-36 scores except emotional role limitations (Z-range -7.21 to -3.34). VFD-patients were less impaired in SF-36 scores than general stroke patients one month post lesion (6/8 subscales) but had lower SF-36 scores compared to stroke patients six months post lesion (5/8 subscales). Visual acuity significantly correlated with NEI-VFQ scores (r-range 0.27 to 0.48) and VFD-type with SF-36 mental subscales (r-range -0.26 to -0.36).</p> <p>Conclusions</p> <p>VFD-patients showed substantial reductions of VRQoL and HRQoL compared to healthy normals, but better HRQoL compared to stroke patients one month post lesion. VFD-patients (although their lesion age was four times higher) had significantly lower HRQoL than a general stroke population at six months post-stroke. This indicates that the stroke-related subjective level of HRQoL impairment is significantly exacerbated by VFD. While VRQoL was primarily influenced by visual acuity, mental components of HRQoL were influenced by VFD-type with larger VFD being associated with more distress.</p> |
| first_indexed | 2024-04-12T21:11:31Z |
| format | Article |
| id | doaj.art-669006a2e20c422ca193b64d3bb4a250 |
| institution | Directory Open Access Journal |
| issn | 1477-7525 |
| language | English |
| last_indexed | 2024-04-12T21:11:31Z |
| publishDate | 2010-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Health and Quality of Life Outcomes |
| spelling | doaj.art-669006a2e20c422ca193b64d3bb4a2502022-12-22T03:16:35ZengBMCHealth and Quality of Life Outcomes1477-75252010-03-01813310.1186/1477-7525-8-33Vision-related quality of life in first stroke patients with homonymous visual field defectsSabel Bernhard AFranke Gabriele HGall Carolin<p>Abstract</p> <p>Background</p> <p>To evaluate vision-related and health-related quality of life (VRQoL, HRQoL) in first stroke patients with homonymous visual field defects (VFD) with respect to the extent of the lesion. Since VFD occur in approximately 10% of stroke patients the main purpose of the study was to investigate the additional impact of VFD in stroke patients hypothesizing that VFD causes diminished VRQoL.</p> <p>Methods</p> <p>In 177 first stroke patients with persisting VFD 2.5 years after posterior-parietal lesions VRQoL was assessed by the National-Eye-Institute-Visual-Functioning-Questionnaire (NEI-VFQ) and HRQoL by the Medical-Outcome-Study Short-Form-36 Health-Survey (SF-36). Questionnaire results of VFD-patients were compared with age- and sex-matched healthy controls and with general non-selected stroke samples as published elsewhere. VFD-type and visual acuity were partially correlated with questionnaire results.</p> <p>Results</p> <p>Compared to healthy controls VFD-patients had lower NEI-VFQ scores except ocular pain (Z-range -11.34 to -3.35) and lower SF-36 scores except emotional role limitations (Z-range -7.21 to -3.34). VFD-patients were less impaired in SF-36 scores than general stroke patients one month post lesion (6/8 subscales) but had lower SF-36 scores compared to stroke patients six months post lesion (5/8 subscales). Visual acuity significantly correlated with NEI-VFQ scores (r-range 0.27 to 0.48) and VFD-type with SF-36 mental subscales (r-range -0.26 to -0.36).</p> <p>Conclusions</p> <p>VFD-patients showed substantial reductions of VRQoL and HRQoL compared to healthy normals, but better HRQoL compared to stroke patients one month post lesion. VFD-patients (although their lesion age was four times higher) had significantly lower HRQoL than a general stroke population at six months post-stroke. This indicates that the stroke-related subjective level of HRQoL impairment is significantly exacerbated by VFD. While VRQoL was primarily influenced by visual acuity, mental components of HRQoL were influenced by VFD-type with larger VFD being associated with more distress.</p>http://www.hqlo.com/content/8/1/33 |
| spellingShingle | Sabel Bernhard A Franke Gabriele H Gall Carolin Vision-related quality of life in first stroke patients with homonymous visual field defects Health and Quality of Life Outcomes |
| title | Vision-related quality of life in first stroke patients with homonymous visual field defects |
| title_full | Vision-related quality of life in first stroke patients with homonymous visual field defects |
| title_fullStr | Vision-related quality of life in first stroke patients with homonymous visual field defects |
| title_full_unstemmed | Vision-related quality of life in first stroke patients with homonymous visual field defects |
| title_short | Vision-related quality of life in first stroke patients with homonymous visual field defects |
| title_sort | vision related quality of life in first stroke patients with homonymous visual field defects |
| url | http://www.hqlo.com/content/8/1/33 |
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