Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients

We report a case of a 29-year-old woman admitted twice to our hospital with diabetic ketoacidosis (DKA) within 45 days following her bariatric surgery. The first admission required intensive care during her postoperative days after bariatric surgery. Subsequently, she continued to report high level...

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Main Authors: Philip Moseley, Mohamed H Ahmed, Henry Owles
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-06-01
Series:Journal of Laboratory Physicians
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731139
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author Philip Moseley
Mohamed H Ahmed
Henry Owles
author_facet Philip Moseley
Mohamed H Ahmed
Henry Owles
author_sort Philip Moseley
collection DOAJ
description We report a case of a 29-year-old woman admitted twice to our hospital with diabetic ketoacidosis (DKA) within 45 days following her bariatric surgery. The first admission required intensive care during her postoperative days after bariatric surgery. Subsequently, she continued to report high level of ketones on a daily basis. At her second admission, she presented with all three criteria of DKA. She was treated with a standard protocol for DKA, but ketones plasma level remained high despite significant improvement in pH and glycemic control. The administration of thiamine replacement was associated with normalization of the hyperketonemia. Thiamine deficiency can be associated with bariatric surgery and can lead to high ketone level in individuals with type 1 diabetes.
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spelling doaj.art-66967383163a4d4594c7b44115f8bc5a2022-12-21T22:52:05ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Laboratory Physicians0974-27270974-78262021-06-01130328028210.1055/s-0041-1731139Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of MicronutrientsPhilip Moseley0Mohamed H Ahmed1Henry Owles2Department of Medicine, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, United KingdomDepartment of Medicine, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, United KingdomDepartment of Medicine, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, United KingdomWe report a case of a 29-year-old woman admitted twice to our hospital with diabetic ketoacidosis (DKA) within 45 days following her bariatric surgery. The first admission required intensive care during her postoperative days after bariatric surgery. Subsequently, she continued to report high level of ketones on a daily basis. At her second admission, she presented with all three criteria of DKA. She was treated with a standard protocol for DKA, but ketones plasma level remained high despite significant improvement in pH and glycemic control. The administration of thiamine replacement was associated with normalization of the hyperketonemia. Thiamine deficiency can be associated with bariatric surgery and can lead to high ketone level in individuals with type 1 diabetes.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731139thiaminebariatric surgerydiabetes
spellingShingle Philip Moseley
Mohamed H Ahmed
Henry Owles
Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
Journal of Laboratory Physicians
thiamine
bariatric surgery
diabetes
title Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_full Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_fullStr Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_full_unstemmed Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_short Recurrent Diabetic Ketoacidosis following Bariatric Surgery: The Role of Micronutrients
title_sort recurrent diabetic ketoacidosis following bariatric surgery the role of micronutrients
topic thiamine
bariatric surgery
diabetes
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1731139
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AT mohamedhahmed recurrentdiabeticketoacidosisfollowingbariatricsurgerytheroleofmicronutrients
AT henryowles recurrentdiabeticketoacidosisfollowingbariatricsurgerytheroleofmicronutrients