RNA interference technology and Ophthalmic diseases
RNA interference is an important discovery in the field of biology in recent years, which is a gene silencing phenomena of specific sequences induced by double-stranded RNA. RNAi technology becomes perfect and mature increasingly, and has been gradually applied in functional genomics, regulatory mec...
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2014-05-01
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| Series: | Guoji Yanke Zazhi |
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| Online Access: | http://www.ies.net.cn/cn_publish/2014/5/201405017.pdf |
| _version_ | 1819038441422192640 |
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| author | Xian-Jie Qin Yan-Yi Peng |
| author_facet | Xian-Jie Qin Yan-Yi Peng |
| author_sort | Xian-Jie Qin |
| collection | DOAJ |
| description | RNA interference is an important discovery in the field of biology in recent years, which is a gene silencing phenomena of specific sequences induced by double-stranded RNA. RNAi technology becomes perfect and mature increasingly, and has been gradually applied in functional genomics, regulatory mechanisms of gene expression research areas.As an effective tool, RNAi technology in gene therapy of eye disease has also made great progress.This paper briefly reviews the current researches of RNAi technology adopting in corneal endolthelial cells injury and therapies of cataract, glaucoma, neovascular diseases and proliferative vitreoretinopathy. |
| first_indexed | 2024-12-21T08:37:22Z |
| format | Article |
| id | doaj.art-6698a6b8936c440b85886062117a1c96 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-21T08:37:22Z |
| publishDate | 2014-05-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-6698a6b8936c440b85886062117a1c962022-12-21T19:10:02ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232014-05-0114584985110.3980/j.issn.1672-5123.2014.05.17RNA interference technology and Ophthalmic diseasesXian-Jie Qin0Yan-Yi Peng1Guilin Medical University, Guilin 541004, Guangxi Zhuang Autonomous Region, ChinaDepartment of Ophthalmology, Affiliated Hospital of Guilin Medical University, Guilin 541001,Guangxi Zhuang Autonomous Region, ChinaRNA interference is an important discovery in the field of biology in recent years, which is a gene silencing phenomena of specific sequences induced by double-stranded RNA. RNAi technology becomes perfect and mature increasingly, and has been gradually applied in functional genomics, regulatory mechanisms of gene expression research areas.As an effective tool, RNAi technology in gene therapy of eye disease has also made great progress.This paper briefly reviews the current researches of RNAi technology adopting in corneal endolthelial cells injury and therapies of cataract, glaucoma, neovascular diseases and proliferative vitreoretinopathy.http://www.ies.net.cn/cn_publish/2014/5/201405017.pdfRNAi technologycorneal endothelial cells injurycataractglaucomaneovascular diseasesproliferative vitreoretinopathyproliferative vitreoretinopathy |
| spellingShingle | Xian-Jie Qin Yan-Yi Peng RNA interference technology and Ophthalmic diseases Guoji Yanke Zazhi RNAi technology corneal endothelial cells injury cataract glaucoma neovascular diseases proliferative vitreoretinopathy proliferative vitreoretinopathy |
| title | RNA interference technology and Ophthalmic diseases |
| title_full | RNA interference technology and Ophthalmic diseases |
| title_fullStr | RNA interference technology and Ophthalmic diseases |
| title_full_unstemmed | RNA interference technology and Ophthalmic diseases |
| title_short | RNA interference technology and Ophthalmic diseases |
| title_sort | rna interference technology and ophthalmic diseases |
| topic | RNAi technology corneal endothelial cells injury cataract glaucoma neovascular diseases proliferative vitreoretinopathy proliferative vitreoretinopathy |
| url | http://www.ies.net.cn/cn_publish/2014/5/201405017.pdf |
| work_keys_str_mv | AT xianjieqin rnainterferencetechnologyandophthalmicdiseases AT yanyipeng rnainterferencetechnologyandophthalmicdiseases |