A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures
Linear chain molecules play a central role in polymer physics with innumerable industrial applications. They are also ubiquitous constituents of living cells. Here, we highlight the similarities and differences between two distinct ways of viewing a linear chain. We do this, on the one hand, through...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Polymers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4360/16/4/502 |
| _version_ | 1797297136850698240 |
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| author | Tatjana Škrbić Achille Giacometti Trinh X. Hoang Amos Maritan Jayanth R. Banavar |
| author_facet | Tatjana Škrbić Achille Giacometti Trinh X. Hoang Amos Maritan Jayanth R. Banavar |
| author_sort | Tatjana Škrbić |
| collection | DOAJ |
| description | Linear chain molecules play a central role in polymer physics with innumerable industrial applications. They are also ubiquitous constituents of living cells. Here, we highlight the similarities and differences between two distinct ways of viewing a linear chain. We do this, on the one hand, through the lens of simulations for a standard polymer chain of tethered spheres at low and high temperatures and, on the other hand, through published experimental data on an important class of biopolymers, proteins. We present detailed analyses of their local and non-local structures as well as the maps of their closest contacts. We seek to reconcile the startlingly different behaviors of the two types of chains based on symmetry considerations. |
| first_indexed | 2024-03-07T22:16:58Z |
| format | Article |
| id | doaj.art-669ae02c62b041fc8b5831fb6854de86 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-07T22:16:58Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-669ae02c62b041fc8b5831fb6854de862024-02-23T15:32:17ZengMDPI AGPolymers2073-43602024-02-0116450210.3390/polym16040502A Tale of Two Chains: Geometries of a Chain Model and Protein Native State StructuresTatjana Škrbić0Achille Giacometti1Trinh X. Hoang2Amos Maritan3Jayanth R. Banavar4Department of Molecular Sciences and Nanosystems, Ca’ Foscari University of Venice, 30170 Venice, ItalyDepartment of Molecular Sciences and Nanosystems, Ca’ Foscari University of Venice, 30170 Venice, ItalyInstitute of Physics, Vietnam Academy of Science and Technology, Hanoi 11108, VietnamDepartment of Physics and Astronomy, University of Padua, 35122 Padua, ItalyDepartment of Physics and Institute for Fundamental Science, University of Oregon, Eugene, OR 97403, USALinear chain molecules play a central role in polymer physics with innumerable industrial applications. They are also ubiquitous constituents of living cells. Here, we highlight the similarities and differences between two distinct ways of viewing a linear chain. We do this, on the one hand, through the lens of simulations for a standard polymer chain of tethered spheres at low and high temperatures and, on the other hand, through published experimental data on an important class of biopolymers, proteins. We present detailed analyses of their local and non-local structures as well as the maps of their closest contacts. We seek to reconcile the startlingly different behaviors of the two types of chains based on symmetry considerations.https://www.mdpi.com/2073-4360/16/4/502symmetrygeometrylocal and non-local structurecontact maps |
| spellingShingle | Tatjana Škrbić Achille Giacometti Trinh X. Hoang Amos Maritan Jayanth R. Banavar A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures Polymers symmetry geometry local and non-local structure contact maps |
| title | A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures |
| title_full | A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures |
| title_fullStr | A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures |
| title_full_unstemmed | A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures |
| title_short | A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures |
| title_sort | tale of two chains geometries of a chain model and protein native state structures |
| topic | symmetry geometry local and non-local structure contact maps |
| url | https://www.mdpi.com/2073-4360/16/4/502 |
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