The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses
Alzheimer's disease (AD) is the most frequent type of dementia, presenting a substantial danger to the health and well-being of the aged population. It has arisen as a significant public health problem with considerable socioeconomic repercussions. Unfortunately, no effective treatments or diag...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2024-09-01
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| Series: | Non-coding RNA Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468054024000581 |
| _version_ | 1797234042905559040 |
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| author | Xiaoben Wu Pengcheng Xia Lei Yang Chao Lu Zhiming Lu |
| author_facet | Xiaoben Wu Pengcheng Xia Lei Yang Chao Lu Zhiming Lu |
| author_sort | Xiaoben Wu |
| collection | DOAJ |
| description | Alzheimer's disease (AD) is the most frequent type of dementia, presenting a substantial danger to the health and well-being of the aged population. It has arisen as a significant public health problem with considerable socioeconomic repercussions. Unfortunately, no effective treatments or diagnostic tools are available for Alzheimer's disease. Despite substantial studies on the pathophysiology of Alzheimer's, the molecular pathways underpinning its development remain poorly understood. Long non-coding RNAs (lncRNAs) vary in size from 200 nucleotides to over 100 kilobytes and have been found to play critical roles in various vital biological processes that play critical in developing Alzheimer's disease. This review intends to examine the functions of long non-coding RNAs in diagnosing and treating Alzheimer's disease and their participation in immunological responses associated with AD. |
| first_indexed | 2024-04-24T16:25:47Z |
| format | Article |
| id | doaj.art-669b4c86861444989f99d6537de6e4cd |
| institution | Directory Open Access Journal |
| issn | 2468-0540 |
| language | English |
| last_indexed | 2024-04-24T16:25:47Z |
| publishDate | 2024-09-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Non-coding RNA Research |
| spelling | doaj.art-669b4c86861444989f99d6537de6e4cd2024-03-31T04:37:51ZengKeAi Communications Co., Ltd.Non-coding RNA Research2468-05402024-09-0193659666The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responsesXiaoben Wu0Pengcheng Xia1Lei Yang2Chao Lu3Zhiming Lu4Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China; Corresponding author.Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, ChinaDepartment of Medical Engineering, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, ChinaDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China; Corresponding author.Department of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China; Corresponding author.Alzheimer's disease (AD) is the most frequent type of dementia, presenting a substantial danger to the health and well-being of the aged population. It has arisen as a significant public health problem with considerable socioeconomic repercussions. Unfortunately, no effective treatments or diagnostic tools are available for Alzheimer's disease. Despite substantial studies on the pathophysiology of Alzheimer's, the molecular pathways underpinning its development remain poorly understood. Long non-coding RNAs (lncRNAs) vary in size from 200 nucleotides to over 100 kilobytes and have been found to play critical roles in various vital biological processes that play critical in developing Alzheimer's disease. This review intends to examine the functions of long non-coding RNAs in diagnosing and treating Alzheimer's disease and their participation in immunological responses associated with AD.http://www.sciencedirect.com/science/article/pii/S2468054024000581Alzheimer's diseaseLong non-coding RNADiagnosisTreatmentProgression |
| spellingShingle | Xiaoben Wu Pengcheng Xia Lei Yang Chao Lu Zhiming Lu The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses Non-coding RNA Research Alzheimer's disease Long non-coding RNA Diagnosis Treatment Progression |
| title | The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses |
| title_full | The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses |
| title_fullStr | The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses |
| title_full_unstemmed | The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses |
| title_short | The roles of long non-coding RNAs in Alzheimer's disease diagnosis, treatment, and their involvement in Alzheimer's disease immune responses |
| title_sort | roles of long non coding rnas in alzheimer s disease diagnosis treatment and their involvement in alzheimer s disease immune responses |
| topic | Alzheimer's disease Long non-coding RNA Diagnosis Treatment Progression |
| url | http://www.sciencedirect.com/science/article/pii/S2468054024000581 |
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