First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe
Canine cases of relapsing fever (RF) borreliosis have been described in Israel and the USA, where two RF species, <i>Borrelia turicatae</i> and <i>Borrelia hermsii</i>, can cause similar clinical signs to the <i>Borrelia persica</i> in dogs and cats reported from...
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| Format: | Article |
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MDPI AG
2020-08-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/8/8/1251 |
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| author | Gabriele Margos Nikola Pantchev Majda Globokar Javier Lopez Jaume Rodon Leticia Hernandez Heike Herold Noelia Salas Anna Civit Volker Fingerle |
| author_facet | Gabriele Margos Nikola Pantchev Majda Globokar Javier Lopez Jaume Rodon Leticia Hernandez Heike Herold Noelia Salas Anna Civit Volker Fingerle |
| author_sort | Gabriele Margos |
| collection | DOAJ |
| description | Canine cases of relapsing fever (RF) borreliosis have been described in Israel and the USA, where two RF species, <i>Borrelia turicatae</i> and <i>Borrelia hermsii</i>, can cause similar clinical signs to the <i>Borrelia persica</i> in dogs and cats reported from Israel, including fever, lethargy, anorexia, thrombocytopenia, and spirochetemia. In this report, we describe the first clinical cases of two dogs and a cat from Spain (Cordoba, Valencia, and Seville) caused by the RF species <i>Borrelia hispanica.</i> Spirochetes were present in the blood smears of all three animals, and clinical signs included lethargy, pale mucosa, anorexia, cachexia, or mild abdominal respiration. Laboratory findings, like thrombocytopenia in both dogs, may have been caused by co-infecting pathogens (i.e., <i>Babesia vogeli</i>, confirmed in one dog). Anemia was noticed in one of the dogs and in the cat. <i>Borrelia hispanica</i> was confirmed as an infecting agent by molecular analysis of the 16S rRNA locus. Molecular analysis of housekeeping genes and phylogenetic analyses, as well as successful in vitro culture of the feline isolate confirmed the causative agent as <i>B. hispanica</i>. |
| first_indexed | 2024-03-10T17:17:14Z |
| format | Article |
| id | doaj.art-669baaab2a75443996a5a0d9475c8b8c |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T17:17:14Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-669baaab2a75443996a5a0d9475c8b8c2023-11-20T10:27:48ZengMDPI AGMicroorganisms2076-26072020-08-0188125110.3390/microorganisms8081251First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from EuropeGabriele Margos0Nikola Pantchev1Majda Globokar2Javier Lopez3Jaume Rodon4Leticia Hernandez5Heike Herold6Noelia Salas7Anna Civit8Volker Fingerle9German National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, 85764 Oberschleißheim, GermanyIDEXX Laboratories, 70806 Kornwestheim, GermanyIDEXX Laboratories, 70806 Kornwestheim, GermanyIDEXX Laboratories, 08038 Barcelona, SpainIDEXX Laboratories, 08038 Barcelona, SpainIDEXX Laboratories, 08038 Barcelona, SpainBavarian Health and Food Safety Authority, 85764 Oberschleißheim, GermanyIDEXX Laboratories, 08038 Barcelona, SpainIDEXX Laboratories, 08038 Barcelona, SpainGerman National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, 85764 Oberschleißheim, GermanyCanine cases of relapsing fever (RF) borreliosis have been described in Israel and the USA, where two RF species, <i>Borrelia turicatae</i> and <i>Borrelia hermsii</i>, can cause similar clinical signs to the <i>Borrelia persica</i> in dogs and cats reported from Israel, including fever, lethargy, anorexia, thrombocytopenia, and spirochetemia. In this report, we describe the first clinical cases of two dogs and a cat from Spain (Cordoba, Valencia, and Seville) caused by the RF species <i>Borrelia hispanica.</i> Spirochetes were present in the blood smears of all three animals, and clinical signs included lethargy, pale mucosa, anorexia, cachexia, or mild abdominal respiration. Laboratory findings, like thrombocytopenia in both dogs, may have been caused by co-infecting pathogens (i.e., <i>Babesia vogeli</i>, confirmed in one dog). Anemia was noticed in one of the dogs and in the cat. <i>Borrelia hispanica</i> was confirmed as an infecting agent by molecular analysis of the 16S rRNA locus. Molecular analysis of housekeeping genes and phylogenetic analyses, as well as successful in vitro culture of the feline isolate confirmed the causative agent as <i>B. hispanica</i>.https://www.mdpi.com/2076-2607/8/8/1251<i>Borrelia hispanica</i>Europerelapsing feverborreliosiscatdog |
| spellingShingle | Gabriele Margos Nikola Pantchev Majda Globokar Javier Lopez Jaume Rodon Leticia Hernandez Heike Herold Noelia Salas Anna Civit Volker Fingerle First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe Microorganisms <i>Borrelia hispanica</i> Europe relapsing fever borreliosis cat dog |
| title | First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe |
| title_full | First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe |
| title_fullStr | First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe |
| title_full_unstemmed | First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe |
| title_short | First Cases of Natural Infections with <i>Borrelia hispanica</i> in Two Dogs and a Cat from Europe |
| title_sort | first cases of natural infections with i borrelia hispanica i in two dogs and a cat from europe |
| topic | <i>Borrelia hispanica</i> Europe relapsing fever borreliosis cat dog |
| url | https://www.mdpi.com/2076-2607/8/8/1251 |
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