Sequence Variant Analysis of the <i>APOCII</i> Locus among an Arab Cohort

Sequence Variant Analysis of the <i>APOCII</i> Locus among an Arab Cohort

Apolipoprotein CII (ApocII) plays a key role in regulating lipoprotein lipase (LPL) in lipid metabolism and transport. Numerous polymorphisms within <i>APOCII</i> are reportedly associated with type 2 diabetes mellitus (T2DM), dyslipidemia, and aberrant plasma lipid levels. Few studies h...

Full description

Bibliographic Details
Main Authors:	Suzanne A. Al-Bustan, Maryam H. Alrashid, Ahmad E. Al-Serri, Babitha G. Annice, Hussain M. Bahbahani
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	International Journal of Molecular Sciences
Subjects:	<i>APOCII</i> sequencing genetic variants T2DM hypertriglyceridemia Arabs
Online Access:	https://www.mdpi.com/1422-0067/24/22/16293

Similar Items

Association of the lipoprotein lipase and Apolipoprotein C-II gene polymorphisms with risk of dyslipidemia in smokers and non-smokers male
by: Rithab Ibrahim Al-Samawi, et al.
Published: (2022-01-01)

Sequence analysis and variant identification at the APOC3 gene locus indicates association of rs5218 with BMI in a sample of Kuwaiti’s
by: Zainab H. Malalla, et al.
Published: (2019-12-01)

<i>Akkermansia</i>, a Possible Microbial Marker for Poor Glycemic Control in Qataris Children Consuming Arabic Diet—A Pilot Study on Pediatric T1DM in Qatar
by: Arun Prasath Lakshmanan, et al.
Published: (2021-03-01)

Identification and Characterization of Two Novel Compounds: Heterozygous Variants of Lipoprotein Lipase in Two Pedigrees With Type I Hyperlipoproteinemia
by: Shuping Wang, et al.
Published: (2022-07-01)

A Clinical Case of a Homozygous Deletion in the <i>APOA5</i> Gene with Severe Hypertriglyceridemia
by: Petr Andreevich Vasiluev, et al.
Published: (2022-06-01)

A novel LPL intronic variant: g.18704C>A identified by re-sequencing Kuwaiti Arab samples is associated with high-density lipoprotein, very low-density lipoprotein and triglyceride lipid levels.
by: Suzanne A Al-Bustan, et al.
Published: (2018-01-01)

A Review on the Main Phytoconstituents, Traditional Uses, Inventions, and Patent Literature of Gum Arabic Emphasizing <i>Acacia seyal</i>
by: Mohamed A. Ashour, et al.
Published: (2022-02-01)

Population Dynamics of <i>Hyalomma dromedarii</i> on Camels in the United Arab Emirates
by: Nighat Perveen, et al.
Published: (2020-05-01)

<i>In Cis</i> Effect of <i>DMPK</i> Expanded Alleles in Myotonic Dystrophy Type 1 Patients Carrying Variant Repeats at 5′ and 3′ Ends of the CTG Array
by: Virginia Veronica Visconti, et al.
Published: (2023-06-01)

Functional Analysis of the <i>PCCA</i> and <i>PCCB</i> Gene Variants Predicted to Affect Splicing
by: Igor Bychkov, et al.
Published: (2021-04-01)

The Genetic Spectrum of Familial Hypertriglyceridemia in Oman
by: Khalid Al-Waili, et al.
Published: (2022-05-01)

Identification and Characterization of Variants in Intron 6 of the <i>LPL</i> Gene Locus among a Sample of the Kuwaiti Population
by: Reem T. Al-Shammari, et al.
Published: (2022-04-01)

Kinetics of Arab Light Crude Oil Degradation by <i>Pseudomonas</i> and <i>Bacillus</i> Strains
by: Carlos Costa, et al.
Published: (2022-11-01)

Griscelli syndrome
by: Kumar T, et al.
Published: (2006-01-01)

The Effect of Gum Arabic (<i>Acacia senegal</i>) on Cardiovascular Risk Factors and Gastrointestinal Symptoms in Adults at Risk of Metabolic Syndrome: A Randomized Clinical Trial
by: Amjad H. Jarrar, et al.
Published: (2021-01-01)

Hypertriglyceridemia Induced Acute Pancreatitis Caused by a Novel LIPC Gene Variant in a Pediatric Patient
by: Laura Balanescu, et al.
Published: (2022-02-01)

ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice
by: Emanuel Voyiaziakis, et al.
Published: (1998-02-01)

Characterization of <i>Moringa oleifera</i> Leaf Powder Extract Encapsulated in Maltodextrin and/or Gum Arabic Coatings
by: Toyosi T. George, et al.
Published: (2021-12-01)

Artificial Neural Networks Model for Predicting Type 2 Diabetes Mellitus Based on <i>VDR</i> Gene <i>FokI</i> Polymorphism, Lipid Profile and Demographic Data
by: Ma’mon M. Hatmal, et al.
Published: (2020-08-01)

Molecular Detection of <i>Candidatus Anaplasma camelii</i> in Naturally Infected Dromedary Camels (<i>Camelus dromedarius</i>) in Abu Dhabi Emirate, United Arab Emirates, 2019–2023
by: Hassan Zackaria Ali Ishag, et al.
Published: (2024-03-01)

Haplotype Analysis Sheds Light on the Genetic Evolution of the Powdery Mildew Resistance Locus <i>Pm60</i> in <i>Triticum</i> Species
by: Xuhui Huang, et al.
Published: (2023-02-01)

Pathogenic <i>APC</i> Variants in Latvian Familial Adenomatous Polyposis Patients
by: Zanda Daneberga, et al.
Published: (2019-09-01)

Improvement of Hypertriglyceridemia by Roasted <i>Nelumbinis folium</i> in High Fat/High Cholesterol Diet Rat Model
by: Hye Yoom Kim, et al.
Published: (2020-12-01)

A Novel Homozygous Founder Variant of <i>RTN4IP1</i> in Two Consanguineous Saudi Families
by: Mazhor Aldosary, et al.
Published: (2022-10-01)

Improving the Retrieval of Arabic Web Search Results Using Enhanced <i>k</i>-Means Clustering Algorithm
by: Amjad F. Alsuhaim, et al.
Published: (2021-04-01)

Whole Locus Sequencing Identifies a Prevalent Founder Deep Intronic <i>RPGRIP1</i> Pathologic Variant in the French Leber Congenital Amaurosis Cohort
by: Isabelle Perrault, et al.
Published: (2021-02-01)

Arabic Language and the Concept of I’jaz al-Qur’an (Critics to Louwis ‘Awad’s thoughts/Bahasa Arab dan Konsep I’jaz al-Qur’an (Kritik Pemikiran Louwis ‘Awad)
by: Rahadian Kurniawan, et al.
Published: (2021-05-01)

DYSLIPIDEMIA IN TYPE 2 DIABETES MELLITUS: MORE ATHEROGENIC LIPID PROFILE IN WOMEN
by: M. Nakhjavani, et al.
Published: (2006-04-01)

DYSLIPIDEMIA IN TYPE 2 DIABETES MELLITUS: MORE ATHEROGENIC LIPID PROFILE IN WOMEN
by: M. Nakhjavani, et al.
Published: (2006-06-01)

A Rare Mutation in <i>LMNB2</i> Associated with Lipodystrophy Drives Premature Cell Senescence
by: Alice-Anaïs Varlet, et al.
Published: (2021-12-01)

The Relationship between Type 2 Diabetes, Differentiation of Self, and Emotional Distress: Jews and Arabs in Israel
by: Ora Peleg
Published: (2021-12-01)

Effect of Inulin Intervention on Metabolic Control and Methylation of <i>INS</i> and <i>IRS1</i> Genes in Patients with Type 2 Diabetes Mellitus
by: Ollin Celeste Martínez-Ramírez, et al.
Published: (2022-12-01)

Tigecycline Sensitivity Reduction in <i>Escherichia coli</i> Due to Widely Distributed <i>tet</i>(A) Variants
by: Shan Zhang, et al.
Published: (2023-12-01)

Vitamin B12 Deficiency in Patients with Diabetes on Metformin: Arab Countries
by: Jwaher Haji Alhaji
Published: (2022-05-01)

Allele-Specific Epigenetic Regulation of <i>FURIN</i> Expression at a Coronary Artery Disease Susceptibility Locus
by: Wei Yang, et al.
Published: (2023-06-01)

Deciphering the Variants Located in the <i>MIR196A2</i>, <i>MIR146A</i>, and <i>MIR423</i> with Type-2 Diabetes Mellitus in Pakistani Population
by: Muhammad Sohail Khan, et al.
Published: (2021-04-01)

Microbial Communities in Home-Made and Commercial <i>Kefir</i> and Their Hypoglycemic Properties
by: Birsen Yilmaz, et al.
Published: (2022-10-01)

The relationship between Arabism and Islam
by: Hashim AlMalah
Published: (1981-09-01)

Ethanol Extract of <i>Pinus koraiensis</i> Leaves Mitigates High Fructose-Induced Hepatic Triglyceride Accumulation and Hypertriglyceridemia
by: Min-Ho Lee, et al.
Published: (2022-07-01)

Delineating Novel and Known Pathogenic Variants in <i>TYR</i>, <i>OCA2</i> and <i>HPS-1</i> Genes in Eight Oculocutaneous Albinism (OCA) Pakistani Families
by: Muhammad Shakil, et al.
Published: (2022-03-01)