The Female Reproductive Tract Microbiota: Friends and Foe
We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attentio...
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| Format: | Article |
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MDPI AG
2023-06-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/6/1313 |
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| author | Lokesh Kumar Monika Dwivedi Natasha Jain Pranali Shete Subhash Solanki Rahul Gupta Ashish Jain |
| author_facet | Lokesh Kumar Monika Dwivedi Natasha Jain Pranali Shete Subhash Solanki Rahul Gupta Ashish Jain |
| author_sort | Lokesh Kumar |
| collection | DOAJ |
| description | We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attention. Advanced molecular sequencing techniques have revealed a remarkable diversity of the organ-specific microbiota populations, including in the reproductive tract. Currently, the goal of researchers has shifted to generate and perceive the molecular data of those hidden travelers of our body and harness them for the betterment of human health. Recently, microbial communities of the lower and upper reproductive tract and their correlation with the implication in reproductive health and disease have been extensively studied. Many intrinsic and extrinsic factors influences the female reproductive tract microbiota (FRTM) that directly affects the reproductive health. It is now believed that FRTM dominated by <i>Lactobacilli</i> may play an essential role in obstetric health beyond the woman’s intimate comfort and well-being. Women with altered microbiota may face numerous health-related issues. Altered microbiota can be manipulated and restored to their original shape to re-establish normal reproductive health. The aim of the present review is to summarize the FRTM functional aspects that influence reproductive health. |
| first_indexed | 2024-03-11T02:14:25Z |
| format | Article |
| id | doaj.art-66a5a678c6d54ebea24bef00c759b116 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-11T02:14:25Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-66a5a678c6d54ebea24bef00c759b1162023-11-18T11:17:34ZengMDPI AGLife2075-17292023-06-01136131310.3390/life13061313The Female Reproductive Tract Microbiota: Friends and FoeLokesh Kumar0Monika Dwivedi1Natasha Jain2Pranali Shete3Subhash Solanki4Rahul Gupta5Ashish Jain6Genus Breeding India Pvt Ltd., Pune 411005, Maharashtra, IndiaDepartment of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra 835215, Jharkhand, IndiaDepartment of Biotechnology, Chaudhary Charan Singh University, Meerut 250001, Uttar Pradesh, IndiaDepartment of Microbiology, Smt. CHM College, University of Mumbai, Ulhasnagar 421003, Maharashtra, IndiaGenus Breeding India Pvt Ltd., Pune 411005, Maharashtra, IndiaGenus Breeding India Pvt Ltd., Pune 411005, Maharashtra, IndiaDepartment of Microbiology, Smt. CHM College, University of Mumbai, Ulhasnagar 421003, Maharashtra, IndiaWe do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attention. Advanced molecular sequencing techniques have revealed a remarkable diversity of the organ-specific microbiota populations, including in the reproductive tract. Currently, the goal of researchers has shifted to generate and perceive the molecular data of those hidden travelers of our body and harness them for the betterment of human health. Recently, microbial communities of the lower and upper reproductive tract and their correlation with the implication in reproductive health and disease have been extensively studied. Many intrinsic and extrinsic factors influences the female reproductive tract microbiota (FRTM) that directly affects the reproductive health. It is now believed that FRTM dominated by <i>Lactobacilli</i> may play an essential role in obstetric health beyond the woman’s intimate comfort and well-being. Women with altered microbiota may face numerous health-related issues. Altered microbiota can be manipulated and restored to their original shape to re-establish normal reproductive health. The aim of the present review is to summarize the FRTM functional aspects that influence reproductive health.https://www.mdpi.com/2075-1729/13/6/1313<i>Lactobacillus</i>lactic acidmicrobiotaprobioticsreproductive healthvagina |
| spellingShingle | Lokesh Kumar Monika Dwivedi Natasha Jain Pranali Shete Subhash Solanki Rahul Gupta Ashish Jain The Female Reproductive Tract Microbiota: Friends and Foe Life <i>Lactobacillus</i> lactic acid microbiota probiotics reproductive health vagina |
| title | The Female Reproductive Tract Microbiota: Friends and Foe |
| title_full | The Female Reproductive Tract Microbiota: Friends and Foe |
| title_fullStr | The Female Reproductive Tract Microbiota: Friends and Foe |
| title_full_unstemmed | The Female Reproductive Tract Microbiota: Friends and Foe |
| title_short | The Female Reproductive Tract Microbiota: Friends and Foe |
| title_sort | female reproductive tract microbiota friends and foe |
| topic | <i>Lactobacillus</i> lactic acid microbiota probiotics reproductive health vagina |
| url | https://www.mdpi.com/2075-1729/13/6/1313 |
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