MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy.

MiR-145 expression and rare NOTCH1 variants in bicuspid aortic valve-associated aortopathy.

MicroRNAs (miRNAs) may serve as elegant tool to improve risk stratification in bicuspid aortic valve (BAV)-associated aortopathy. However, the exact pathogenetic pathway by which miRNAs impact aortopathy progression is unknown. Herewith, we aimed to analyze the association between circulating miRNAs...

Full description

Bibliographic Details
Main Authors:	Evaldas Girdauskas, Johannes Petersen, Niklas Neumann, Martin Ungelenk, Ingo Kurth, Hermann Reichenspurner, Tanja Zeller
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2018-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC6066209?pdf=render

Similar Items

Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy
by: Ali Fatehi Hassanabad, et al.
Published: (2022-08-01)

Pathogenic Mechanisms of Bicuspid Aortic Valve Aortopathy
by: Noor M. Yassine, et al.
Published: (2017-09-01)

Aortopathy pathophysiology features in patients with bicuspid aortic valve.
by: Arystan Seidalin, et al.
Published: (2016-09-01)

Evolving Surgical Approaches to Bicuspid Aortic Valve Associated Aortopathy
by: Ali Fatehi Hassanabad, et al.
Published: (2019-03-01)

Molecular insights into bicuspid aortic valve development and the associated aortopathy
by: Nikhita Bolar, et al.
Published: (2017-11-01)

Bicuspid aortic valve associated aortopathy: a genetic disease
by: Gibran Minero, et al.
Published: (2015-02-01)

Bicuspid aortic valve associated aortopathy: a genetic disease?
by: Ciro Bancone, et al.
Published: (2015-02-01)

Aortic root aortopathy in bicuspid aortic valve associated with high genetic risk
by: Mingjia Ma, et al.
Published: (2021-08-01)

Inherited aortopathy assessment in relatives of patients with a bicuspid aortic valve
by: Bissell, M, et al.
Published: (2017)

Aortic Valve Dysfunction and Aortopathy Based on the Presence of Raphe in Patients with Bicuspid Aortic Valve Disease
by: Yu Zhang, et al.
Published: (2023-08-01)

4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease
by: Alexander Lenz, et al.
Published: (2020-04-01)

Evaluation of relationship between bicuspid aortic valve phenotype with valve dysfunction and associated aortopathy
by: Mehrnoush Toufan Tabrizi, et al.
Published: (2018-12-01)

Evolution of Precision Medicine and Surgical Strategies for Bicuspid Aortic Valve-Associated Aortopathy
by: Ali Fatehi Hassanabad, et al.
Published: (2017-07-01)

Surgical Aortic Valve Replacement with Concomitant Aortic Surgery in Patients with Purely Bicuspid Aortic Valve and Associated Aortopathy
by: Mevlüt Çelik, et al.
Published: (2021-02-01)

Integrated Aortic-Valve-And-Ascending-Aortic Replacement vs. Partial Replacement in Bicuspid Aortic Valve-Related Aortopathy
by: Mi Chen, et al.
Published: (2021-12-01)

Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women
by: Anders Franco-Cereceda, et al.
Published: (2021-12-01)

Bicuspid Aortic Stenosis with and without Aortopathy: Considerations for Surgical Aortic Valve Replacement versus Transcatheter Aortic Valve Replacement
by: Arthur J Lee, et al.
Published: (2022-08-01)

Emerging imaging and circulating biomarkers in relation to underlying mechanisms in Bicuspid Aortic Valve aortopathy
by: Hamza M Ahmad, et al.
Published: (2025-06-01)

Thoracic aortopathy in Marfan syndrome overlaps with mechanisms seen in bicuspid aortic valve disease
by: Nimrat Grewal, et al.
Published: (2023-02-01)

Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model
by: María Teresa Soto-Navarrete, et al.
Published: (2022-08-01)

Disturbed nitric oxide signalling gives rise to congenital bicuspid aortic valve and aortopathy
by: Joshua C. Peterson, et al.
Published: (2020-09-01)

Rare Presentation of Sinus of Valsalva Aneurysm Treated by Aortic Valve Reimplantation Technique
by: Johannes Petersen, et al.
Published: (2021-12-01)

TIMP3 and TIMP1 are risk genes for bicuspid aortic valve and aortopathy in Turner syndrome.
by: Holly Corbitt, et al.
Published: (2018-10-01)

The genetic, molecular, and hemodynamic basis of bicuspid aortic valve aortopathy: A contemporary narrative review
by: Joseph Burns, et al.
Published: (2022-06-01)

Characteristics of Carotid Artery Structure and Mechanical Function and Their Relationships with Aortopathy in Patients with Bicuspid Aortic Valves
by: Mihyun Kim, et al.
Published: (2017-08-01)

Endogenous Reference Genes for Gene Expression Studies on Bicuspid Aortic Valve Associated Aortopathy in Humans.
by: Oliver J Harrison, et al.
Published: (2016-01-01)

Methods: Aortic wall deformation assessment by ultrafast ultrasound imaging: Application to bicuspid aortic valve associated aortopathy
by: Guillaume Goudot, et al.
Published: (2023-03-01)

Progression of ascending aortopathy may not occur after transcatheter aortic valve replacement in severe bicuspid aortic stenosis
by: Ji-Hyun Jung, et al.
Published: (2021-03-01)

Dysregulation of Endothelial Nitric Oxide Synthase Does Not Depend on Hemodynamic Alterations in Bicuspid Aortic Valve Aortopathy
by: Simon Gauer, et al.
Published: (2020-09-01)

Thoracic aortopathy in Turner syndrome and the influence of bicuspid aortic valves and blood pressure: a CMR study
by: Hager Alfred, et al.
Published: (2010-03-01)

A Segmental Approach from Molecular Profiling to Medical Imaging to Study Bicuspid Aortic Valve Aortopathy
by: Froso Sophocleous, et al.
Published: (2022-11-01)

Relation of Bicuspid Aortic Valve Morphology to the Dilatation Pattern of the Proximal Aorta: Focus on the Transvalvular Flow
by: Evaldas Girdauskas, et al.
Published: (2012-01-01)

Differences between echocardiography and cardiac nuclear magnetic resonance parameters in children with bicuspid aortic valve-related aortopathy
by: Stasa Krasic, et al.
Published: (2024-11-01)

Surgical treatment of mild to moderately dilated ascending aorta in bicuspid aortic valve aortopathy: the art of safety and simplicity
by: Peng Zhu, et al.
Published: (2020-01-01)

Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
by: Jiao Jiao, et al.
Published: (2016-08-01)

Physical and Mental Recovery after Aortic Valve Surgery in Non-Elderly Patients: Native Valve-Preserving Surgery vs. Prosthetic Valve Replacement
by: Theresa Holst, et al.
Published: (2023-03-01)

Editorial: The Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from “Omics”, Models of Disease and Emergent Technologies
by: Amalia Forte, et al.
Published: (2017-12-01)

Bicuspid Valve Aortopathy: Is It Reasonable to Define a Different Surgical Cutoff Based on Different Aortic Wall Mechanical Properties Compared to Those of the Tricuspid Valve?
by: Pasquale Totaro, et al.
Published: (2024-10-01)

P129 Arterial Stiffness in Bicuspid or Tricuspid Aortic Valve Aortopathy Using Magnetic Resonance Imaging: Crossing the Physical and Hemodynamic limits?
by: Ariel Pascaner, et al.
Published: (2020-02-01)

A Comprehensive Review of Management Strategies for Bicuspid Aortic Valve (BAV): Exploring Epidemiology, Aetiology, Aortopathy, and Interventions in Light of Recent Guidelines
by: Halil Ibrahim Bulut, et al.
Published: (2023-09-01)