A protein prioritization approach tailored for the FA/BRCA pathway.
Fanconi anemia (FA) is a heterogeneous recessive disorder associated with a markedly elevated risk to develop cancer. To date sixteen FA genes have been identified, three of which predispose heterozygous mutation carriers to breast cancer. The FA proteins work together in a genome maintenance pathwa...
Main Authors: | Anneke Haitjema, Bernd W Brandt, Najim Ameziane, Patrick May, Jaap Heringa, Johan P de Winter, Hans Joenje, Josephine C Dorsman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3631253?pdf=render |
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