The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View
Dilated cardiomyopathies (DCMs) are a heterogenous group of primary myocardial diseases, representing one of the leading causes of heart failure, and the main indication for heart transplantation. While the degree of left ventricular dilation and dysfunction are two key determinants of adverse outco...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Journal of Cardiovascular Development and Disease |
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| Online Access: | https://www.mdpi.com/2308-3425/9/10/359 |
| _version_ | 1797407106515599360 |
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| author | Maria L. Iovănescu Diana R. Florescu Andreea S. Marcu Ionuț Donoiu Sebastian Militaru Cristina Florescu Octavian Istrătoaie Constantin Militaru |
| author_facet | Maria L. Iovănescu Diana R. Florescu Andreea S. Marcu Ionuț Donoiu Sebastian Militaru Cristina Florescu Octavian Istrătoaie Constantin Militaru |
| author_sort | Maria L. Iovănescu |
| collection | DOAJ |
| description | Dilated cardiomyopathies (DCMs) are a heterogenous group of primary myocardial diseases, representing one of the leading causes of heart failure, and the main indication for heart transplantation. While the degree of left ventricular dilation and dysfunction are two key determinants of adverse outcomes in DCM patients, right ventricular (RV) remodeling and dysfunction further negatively influence patient prognosis. Consequently, RV functional assessment and diagnosing RV involvement by using an integrative approach based on multimodality imaging is of paramount importance in the evaluation of DCM patients and provides incremental prognostic and therapeutic information. Transthoracic echocardiography remains the first-line imaging modality used for the assessment of the RV, and newer techniques such as speckle-tracking and three-dimensional echocardiography significantly improve its diagnostic and prognostic accuracy. Nonetheless, cardiac magnetic resonance (CMR) is considered the gold standard imaging modality for the evaluation of RV size and function, and all DCM patients should be evaluated by CMR at least once. Accordingly, this review provides a comprehensive overview of the anatomy and function of the RV, and the pathophysiology, diagnosis, and prognostic value of RV dysfunction in DCM patients, based on traditional and novel imaging techniques. |
| first_indexed | 2024-03-09T03:36:28Z |
| format | Article |
| id | doaj.art-66ab6f5b61284c449b04e150f39bdd47 |
| institution | Directory Open Access Journal |
| issn | 2308-3425 |
| language | English |
| last_indexed | 2024-03-09T03:36:28Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-66ab6f5b61284c449b04e150f39bdd472023-12-03T14:48:12ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-10-0191035910.3390/jcdd9100359The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of ViewMaria L. Iovănescu0Diana R. Florescu1Andreea S. Marcu2Ionuț Donoiu3Sebastian Militaru4Cristina Florescu5Octavian Istrătoaie6Constantin Militaru7Department of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaClinical Emergency County Hospital of Craiova, 200642 Craiova, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Cardiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDilated cardiomyopathies (DCMs) are a heterogenous group of primary myocardial diseases, representing one of the leading causes of heart failure, and the main indication for heart transplantation. While the degree of left ventricular dilation and dysfunction are two key determinants of adverse outcomes in DCM patients, right ventricular (RV) remodeling and dysfunction further negatively influence patient prognosis. Consequently, RV functional assessment and diagnosing RV involvement by using an integrative approach based on multimodality imaging is of paramount importance in the evaluation of DCM patients and provides incremental prognostic and therapeutic information. Transthoracic echocardiography remains the first-line imaging modality used for the assessment of the RV, and newer techniques such as speckle-tracking and three-dimensional echocardiography significantly improve its diagnostic and prognostic accuracy. Nonetheless, cardiac magnetic resonance (CMR) is considered the gold standard imaging modality for the evaluation of RV size and function, and all DCM patients should be evaluated by CMR at least once. Accordingly, this review provides a comprehensive overview of the anatomy and function of the RV, and the pathophysiology, diagnosis, and prognostic value of RV dysfunction in DCM patients, based on traditional and novel imaging techniques.https://www.mdpi.com/2308-3425/9/10/359right ventricular dysfunctiondilated cardiomyopathyechocardiographymulti-modality imaging |
| spellingShingle | Maria L. Iovănescu Diana R. Florescu Andreea S. Marcu Ionuț Donoiu Sebastian Militaru Cristina Florescu Octavian Istrătoaie Constantin Militaru The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View Journal of Cardiovascular Development and Disease right ventricular dysfunction dilated cardiomyopathy echocardiography multi-modality imaging |
| title | The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View |
| title_full | The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View |
| title_fullStr | The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View |
| title_full_unstemmed | The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View |
| title_short | The Dysfunctional Right Ventricle in Dilated Cardiomyopathies: Looking from the Right Point of View |
| title_sort | dysfunctional right ventricle in dilated cardiomyopathies looking from the right point of view |
| topic | right ventricular dysfunction dilated cardiomyopathy echocardiography multi-modality imaging |
| url | https://www.mdpi.com/2308-3425/9/10/359 |
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