Targeted Delivery of GP5 Antigen of PRRSV to M Cells Enhances the Antigen-Specific Systemic and Mucosal Immune Responses
Efficient delivery of antigens through oral immunization is a first and critical step for successful induction of mucosal immunity, which can provide protection against pathogens invading the mucosa. Membranous/microfold cells (M cells) within the mucosa can transcytose internalized antigen without...
Main Authors: | Luping Du, Zhengyu Yu, Fengjiao Pang, Xiangwei Xu, Aihua Mao, Wanzhe Yuan, Kongwang He, Bin Li |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-01-01
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Series: | Frontiers in Cellular and Infection Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fcimb.2018.00007/full |
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