Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal
The prevalence of the non-alcoholic fatty liver disease has reached major proportions, being estimated to affect one-quarter of the global population. The reference techniques, which include liver biopsy and the magnetic resonance imaging proton density fat fraction, have objective practical and fin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/10/2287 |
| _version_ | 1797473897709305856 |
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| author | Dorotea Bozic Kristian Podrug Ivana Mikolasevic Ivica Grgurevic |
| author_facet | Dorotea Bozic Kristian Podrug Ivana Mikolasevic Ivica Grgurevic |
| author_sort | Dorotea Bozic |
| collection | DOAJ |
| description | The prevalence of the non-alcoholic fatty liver disease has reached major proportions, being estimated to affect one-quarter of the global population. The reference techniques, which include liver biopsy and the magnetic resonance imaging proton density fat fraction, have objective practical and financial limitations to their routine use in the detection and quantification of liver steatosis. Therefore, there has been a rising necessity for the development of new inexpensive, widely applicable and reliable non-invasive diagnostic tools. The controlled attenuation parameter has been considered the point-of-care technique for the assessment of liver steatosis for a long period of time. Recently, many ultrasound (US) system manufacturers have developed proprietary software solutions for the quantification of liver steatosis. Some of these methods have already been extensively tested with very good performance results reported, while others are still under evaluation. This manuscript reviews the currently available US-based methods for diagnosing and grading liver steatosis, including their classification and performance results, with an appraisal of the importance of this armamentarium in daily clinical practice. |
| first_indexed | 2024-03-09T20:23:17Z |
| format | Article |
| id | doaj.art-66afa810e7e84c5989d84f4dfe74de1f |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T20:23:17Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-66afa810e7e84c5989d84f4dfe74de1f2023-11-23T23:42:42ZengMDPI AGDiagnostics2075-44182022-09-011210228710.3390/diagnostics12102287Ultrasound Methods for the Assessment of Liver Steatosis: A Critical AppraisalDorotea Bozic0Kristian Podrug1Ivana Mikolasevic2Ivica Grgurevic3Department of Gastroenterology and Hepatology, University Hospital Center Split, Spinčićeva 1, 21 000 Split, CroatiaDepartment of Gastroenterology and Hepatology, University Hospital Center Split, Spinčićeva 1, 21 000 Split, CroatiaDepartment of Gastroenterology and Hepatology, University Hospital Center Rijeka, Krešimirova 42, 51 000 Rijeka, CroatiaDepartment of Gastroenterology, Hepatology and Clinical Nutrition, University Hospital Dubrava, Avenija Gojka Šuška 6, 10 000 Zagreb, CroatiaThe prevalence of the non-alcoholic fatty liver disease has reached major proportions, being estimated to affect one-quarter of the global population. The reference techniques, which include liver biopsy and the magnetic resonance imaging proton density fat fraction, have objective practical and financial limitations to their routine use in the detection and quantification of liver steatosis. Therefore, there has been a rising necessity for the development of new inexpensive, widely applicable and reliable non-invasive diagnostic tools. The controlled attenuation parameter has been considered the point-of-care technique for the assessment of liver steatosis for a long period of time. Recently, many ultrasound (US) system manufacturers have developed proprietary software solutions for the quantification of liver steatosis. Some of these methods have already been extensively tested with very good performance results reported, while others are still under evaluation. This manuscript reviews the currently available US-based methods for diagnosing and grading liver steatosis, including their classification and performance results, with an appraisal of the importance of this armamentarium in daily clinical practice.https://www.mdpi.com/2075-4418/12/10/2287liver steatosissteatosis quantificationNAFLDultrasound attenuation imagingATI |
| spellingShingle | Dorotea Bozic Kristian Podrug Ivana Mikolasevic Ivica Grgurevic Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal Diagnostics liver steatosis steatosis quantification NAFLD ultrasound attenuation imaging ATI |
| title | Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal |
| title_full | Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal |
| title_fullStr | Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal |
| title_full_unstemmed | Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal |
| title_short | Ultrasound Methods for the Assessment of Liver Steatosis: A Critical Appraisal |
| title_sort | ultrasound methods for the assessment of liver steatosis a critical appraisal |
| topic | liver steatosis steatosis quantification NAFLD ultrasound attenuation imaging ATI |
| url | https://www.mdpi.com/2075-4418/12/10/2287 |
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