The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies

Several species of the genus Tanacetum L. (Asteraceae) spread in the Southestern Europe are traditionally used as medicinal and aromatic plants, including T. vulgare, T. parthenium, T. macrophyllum, T. balsamita, T. poteriifolium. The review is focused on the phytochemical and pharmacological studie...

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Main Authors: Reneta Gevrenova, Vessela Balabanova, Dimitrina Zheleva-Dimitrova, Georgi Momekov
Format: Article
Language:English
Published: Pensoft Publishers 2023-10-01
Series:Pharmacia
Online Access:https://pharmacia.pensoft.net/article/110748/download/pdf/
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author Reneta Gevrenova
Vessela Balabanova
Dimitrina Zheleva-Dimitrova
Georgi Momekov
author_facet Reneta Gevrenova
Vessela Balabanova
Dimitrina Zheleva-Dimitrova
Georgi Momekov
author_sort Reneta Gevrenova
collection DOAJ
description Several species of the genus Tanacetum L. (Asteraceae) spread in the Southestern Europe are traditionally used as medicinal and aromatic plants, including T. vulgare, T. parthenium, T. macrophyllum, T. balsamita, T. poteriifolium. The review is focused on the phytochemical and pharmacological studies of these taxa. Major chemical constituents are acylquinic acids, sesquiterpenes, sesquiterpene lactones, methoxylated flavonoids. An in-depth depiction of more than 100 secondary metabolites was achieved in Tanacetum species by liquid chromatography-high resolution mass spectrometry. The ethnopharmacological studies indicate that species possess antioxidant, enzyme inhibitory and cytotoxic activity along with antimicrobial and antiviral effects. Reports revealed anti-inflamatory and neuromodulatory activity involved in the pharmacological approach in counteracting migraine attacks. Multivariate data analysis allowed the identification of the most discriminant metabolites and bioactivities in the herbal drugs. This review emphasizes T. vulgare, T. macrophyllum, T. balsamita and T. parthenium as potential raw material for health-promoting application in pharmaceutical area.
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spelling doaj.art-66afce84bafb430f9c8aabbe2433334a2023-10-13T08:11:07ZengPensoft PublishersPharmacia2603-557X2023-10-017041067108110.3897/pharmacia.70.e110748110748The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studiesReneta Gevrenova0Vessela Balabanova1Dimitrina Zheleva-Dimitrova2Georgi Momekov3Medical UniversityMedical UniversityMedical UniversityMedical UniversitySeveral species of the genus Tanacetum L. (Asteraceae) spread in the Southestern Europe are traditionally used as medicinal and aromatic plants, including T. vulgare, T. parthenium, T. macrophyllum, T. balsamita, T. poteriifolium. The review is focused on the phytochemical and pharmacological studies of these taxa. Major chemical constituents are acylquinic acids, sesquiterpenes, sesquiterpene lactones, methoxylated flavonoids. An in-depth depiction of more than 100 secondary metabolites was achieved in Tanacetum species by liquid chromatography-high resolution mass spectrometry. The ethnopharmacological studies indicate that species possess antioxidant, enzyme inhibitory and cytotoxic activity along with antimicrobial and antiviral effects. Reports revealed anti-inflamatory and neuromodulatory activity involved in the pharmacological approach in counteracting migraine attacks. Multivariate data analysis allowed the identification of the most discriminant metabolites and bioactivities in the herbal drugs. This review emphasizes T. vulgare, T. macrophyllum, T. balsamita and T. parthenium as potential raw material for health-promoting application in pharmaceutical area.https://pharmacia.pensoft.net/article/110748/download/pdf/
spellingShingle Reneta Gevrenova
Vessela Balabanova
Dimitrina Zheleva-Dimitrova
Georgi Momekov
The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
Pharmacia
title The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
title_full The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
title_fullStr The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
title_full_unstemmed The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
title_short The most promising Southeastern European Tanacetum species: a review of chemical composition and biological studies
title_sort most promising southeastern european tanacetum species a review of chemical composition and biological studies
url https://pharmacia.pensoft.net/article/110748/download/pdf/
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