The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease

The review presents the data of recent studies dealing with cognitive impairments (CI) in patients with Parkinson's disease (PD) and gives their characteristics and epidemiology, the specific features of the pathogenesis and clinical manifestations, as well as current methods for their diagnosi...

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Main Authors: G. N. Akhmadeeva, R. V. Magzhanov, G. N. Tayupova, A. R. Baitimerov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2017-03-01
Series:Неврология, нейропсихиатрия, психосоматика
Subjects:
Online Access:https://nnp.ima-press.net/nnp/article/view/706
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author G. N. Akhmadeeva
R. V. Magzhanov
G. N. Tayupova
A. R. Baitimerov
author_facet G. N. Akhmadeeva
R. V. Magzhanov
G. N. Tayupova
A. R. Baitimerov
author_sort G. N. Akhmadeeva
collection DOAJ
description The review presents the data of recent studies dealing with cognitive impairments (CI) in patients with Parkinson's disease (PD) and gives their characteristics and epidemiology, the specific features of the pathogenesis and clinical manifestations, as well as current methods for their diagnosis and treatment. Moderate CIs (MCIs) occur in 18.9–55% of patients with PD; the prevalence of dementia during a cross-sectional study approaches 30%. The 2007 Movement Disorder Society criteria and algorithm for the diagnosis of dementia in PD and the 2012 criteria and the algorithm for the diagnosis of MCIs allow one to maximally accurately identify these disorders. Only rivastigmine is now recognized as effective in treating CI in PD and recommended for use. Overall, therapies for CI in PD have been inadequately investigated, making it necessary to conduct further large-scale studies.
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spelling doaj.art-66b39f5c55af46b8a178b63ad7aaffc32023-03-13T08:42:16ZrusIMA-PRESS LLCНеврология, нейропсихиатрия, психосоматика2074-27112310-13422017-03-019110110510.14412/2074-2711-2017-1-101-105632The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's diseaseG. N. Akhmadeeva0R. V. Magzhanov1G. N. Tayupova2A. R. Baitimerov3Bashkir State Medical University, Ministry of Health of Russia Republic Consulting and Diagnostic Center of Extrapyramidal Pathology and Botulinum Toxin Therapy, OOO «Medstandart» National Medical HoldingBashkir State Medical University, Ministry of Health of RussiaBashkir State Medical University, Ministry of Health of Russia Republic Consulting and Diagnostic Center of Extrapyramidal Pathology and Botulinum Toxin Therapy, OOO «Medstandart» National Medical HoldingRepublic Consulting and Diagnostic Center of Extrapyramidal Pathology and Botulinum Toxin Therapy, OOO «Medstandart» National Medical HoldingThe review presents the data of recent studies dealing with cognitive impairments (CI) in patients with Parkinson's disease (PD) and gives their characteristics and epidemiology, the specific features of the pathogenesis and clinical manifestations, as well as current methods for their diagnosis and treatment. Moderate CIs (MCIs) occur in 18.9–55% of patients with PD; the prevalence of dementia during a cross-sectional study approaches 30%. The 2007 Movement Disorder Society criteria and algorithm for the diagnosis of dementia in PD and the 2012 criteria and the algorithm for the diagnosis of MCIs allow one to maximally accurately identify these disorders. Only rivastigmine is now recognized as effective in treating CI in PD and recommended for use. Overall, therapies for CI in PD have been inadequately investigated, making it necessary to conduct further large-scale studies.https://nnp.ima-press.net/nnp/article/view/706parkinson's diseasecognitive impairmentsdementia
spellingShingle G. N. Akhmadeeva
R. V. Magzhanov
G. N. Tayupova
A. R. Baitimerov
The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease
Неврология, нейропсихиатрия, психосоматика
parkinson's disease
cognitive impairments
dementia
title The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease
title_full The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease
title_fullStr The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease
title_full_unstemmed The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease
title_short The clinical features, diagnosis, and treatment of cognitive impairments in Parkinson's disease
title_sort clinical features diagnosis and treatment of cognitive impairments in parkinson s disease
topic parkinson's disease
cognitive impairments
dementia
url https://nnp.ima-press.net/nnp/article/view/706
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