Differential cellular and humoral immune responses in immunocompromised individuals following multiple SARS-CoV-2 vaccinations

Differential cellular and humoral immune responses in immunocompromised individuals following multiple SARS-CoV-2 vaccinations

IntroductionThe heterogeneity of the immunocompromised population means some individuals may exhibit variable, weak or reduced vaccine-induced immune responses, leaving them poorly protected from COVID-19 disease despite receiving multiple SARS-CoV-2 vaccinations. There is conflicting data on the im...

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Bibliographic Details
Main Authors: Rhys T. Meredith, Max D. Bermingham, Kirsten Bentley, Sayeh Agah, Abigail Aboagye-Odei, Ross A. R. Yarham, Hayley Mills, Muddassir Shaikh, Neil Hoye, Richard J. Stanton, David R. Chadwick, Maria A. Oliver
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
SARS-CoV-2
vaccine efficacy
immunocompromised cohorts
T cell responses
antibody production
third/fourth doses
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1207313/full

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