Agent-based Modeling of Tumor and Immune System Interactions in Combinational Therapy with Low-dose 5-fluorouracil and Dendritic Cell Vaccine in Melanoma B16F10

Agent-based Modeling of Tumor and Immune System Interactions in Combinational Therapy with Low-dose 5-fluorouracil and Dendritic Cell Vaccine in Melanoma B16F10

This study is designed to present an agent-based model (ABM) to simulate the interactions between tumor cells and the immune system in the melanoma model. The Myeloid-derived Suppressor Cells (MDSCs) and dendritic cells (DCs) are considered in this model as immunosuppressive and antigen-presenting...

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Bibliographic Details
Main Authors: Sarah Rahbar, Sajad Shafiekhani, Armin Allahverdi, Arezoo Jamali, Nasim Kheshtchin, Maryam Ajami, Zahra Mirsanei, Sima Habibi, Bahador Makkiabadi, Jamshid Hadjati, Amir Homayoun Jafari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-04-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Fluorouracil
Melanoma
Myeloid-derived suppressor cells
Tumor microenvironment
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3343

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