Visualizing molecules of functional human profilin

Visualizing molecules of functional human profilin

Profilin-1 (PFN1) is a cytoskeletal protein that regulates the dynamics of actin and microtubule assembly. Thus, PFN1 is essential for the normal division, motility, and morphology of cells. Unfortunately, conventional fusion and direct labeling strategies compromise different facets of PFN1 functio...

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Bibliographic Details
Main Authors: Morgan L Pimm, Xinbei Liu, Farzana Tuli, Jennifer Heritz, Ashley Lojko, Jessica L Henty-Ridilla
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
profilin
actin
microtubules
ALS
Online Access:https://elifesciences.org/articles/76485

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