Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution
Deep eutectic solvents (DES) are promising reaction media where interesting catalytic processes can be carried out. In theory, most of these mixtures are environmentally friendly, being an alternative to traditionally pollutant organic solvents used in several processes related to organic chemistry...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022038555 |
| _version_ | 1797960813067108352 |
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| author | Guillermo Martínez Martínez Gabriela Guillena Townley Rosa María Martínez-Espinosa |
| author_facet | Guillermo Martínez Martínez Gabriela Guillena Townley Rosa María Martínez-Espinosa |
| author_sort | Guillermo Martínez Martínez |
| collection | DOAJ |
| description | Deep eutectic solvents (DES) are promising reaction media where interesting catalytic processes can be carried out. In theory, most of these mixtures are environmentally friendly, being an alternative to traditionally pollutant organic solvents used in several processes related to organic chemistry and biotechnology. However, recent studies show contradictory results regarding their toxicity. The method selected to perform toxicity studies could be significantly conditioned by some of the physical properties displayed by the DESs. Also, the metabolic capabilities of the organisms/cells used to monitor their toxicity are influenced by their physical properties. In this review, relevant physical-chemical properties for toxicity studies are summarized. The advantages/disadvantages of the used tests to monitor their toxicity and biodegradability in connection with the chosen organisms/cells are discussed, shedding light on their limitations. These findings could be taken as a starting point for designing more accurate DESs toxicity studies covering a wider spectrum of organisms and cells to be used as biomodels to monitor environmental pollution caused by DESs. |
| first_indexed | 2024-04-11T00:50:05Z |
| format | Article |
| id | doaj.art-66b83a6d06b340eab550138fae42a761 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-11T00:50:05Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-66b83a6d06b340eab550138fae42a7612023-01-05T08:40:59ZengElsevierHeliyon2405-84402022-12-01812e12567Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollutionGuillermo Martínez Martínez0Gabriela Guillena Townley1Rosa María Martínez-Espinosa2Biochemistry and Molecular Biology Division, Agrochemistry and Biochemistry Department, Faculty of Sciences, Ap. 99, E-03080, Alicante, Spain; Multidisciplinary Institute for Environmental Studies (IMEM), University of Alicante, Ap. 99, E-03080, Alicante, SpainOrganic Chemistry Department and Organic Synthesis Institute (ISO), University of Alicante, Ap. 99, E-03080, Alicante, SpainBiochemistry and Molecular Biology Division, Agrochemistry and Biochemistry Department, Faculty of Sciences, Ap. 99, E-03080, Alicante, Spain; Multidisciplinary Institute for Environmental Studies (IMEM), University of Alicante, Ap. 99, E-03080, Alicante, Spain; Corresponding author.Deep eutectic solvents (DES) are promising reaction media where interesting catalytic processes can be carried out. In theory, most of these mixtures are environmentally friendly, being an alternative to traditionally pollutant organic solvents used in several processes related to organic chemistry and biotechnology. However, recent studies show contradictory results regarding their toxicity. The method selected to perform toxicity studies could be significantly conditioned by some of the physical properties displayed by the DESs. Also, the metabolic capabilities of the organisms/cells used to monitor their toxicity are influenced by their physical properties. In this review, relevant physical-chemical properties for toxicity studies are summarized. The advantages/disadvantages of the used tests to monitor their toxicity and biodegradability in connection with the chosen organisms/cells are discussed, shedding light on their limitations. These findings could be taken as a starting point for designing more accurate DESs toxicity studies covering a wider spectrum of organisms and cells to be used as biomodels to monitor environmental pollution caused by DESs.http://www.sciencedirect.com/science/article/pii/S2405844022038555Deep eutectic solventsNatural deep eutectic solventsEcotoxicityBiodegradabilitySustainability |
| spellingShingle | Guillermo Martínez Martínez Gabriela Guillena Townley Rosa María Martínez-Espinosa Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution Heliyon Deep eutectic solvents Natural deep eutectic solvents Ecotoxicity Biodegradability Sustainability |
| title | Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution |
| title_full | Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution |
| title_fullStr | Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution |
| title_full_unstemmed | Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution |
| title_short | Controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution |
| title_sort | controversy on the toxic nature of deep eutectic solvents and their potential contribution to environmental pollution |
| topic | Deep eutectic solvents Natural deep eutectic solvents Ecotoxicity Biodegradability Sustainability |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022038555 |
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