Dosimetric Analysis of Template-assisted 192Ir-source Hypofractionated Stereotactic Ablative Brachytherapy for Peripheral Lung Cancer

Objective To explore the dose of template-assisted 192Ir source hypofractionated stereotactic brachytherapy (SABT) for peripheral lung cancer. Methods We retrospectively analyzed the dose parameters of GTV and OARs of 28 peripheral lung cancer patients treated with template-assisted 192Ir-source hyp...

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Bibliographic Details
Main Authors: GAO Qin, PANG Haowen, SHI Xiangxiang, REN Peirong, LIN Sheng
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2021-05-01
Series:Zhongliu Fangzhi Yanjiu
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Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2021.20.1051
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Summary:Objective To explore the dose of template-assisted 192Ir source hypofractionated stereotactic brachytherapy (SABT) for peripheral lung cancer. Methods We retrospectively analyzed the dose parameters of GTV and OARs of 28 peripheral lung cancer patients treated with template-assisted 192Ir-source hypofractionated SABT, and compared the dose parameters between SABT with virtual SBRT. Results The Dmean and V150 for the GTV in the SABT plan were significantly higher than those in the SBRT plan (all P < 0.01). For OARs, all dosimetric parameters in the SABT plan were significantly lower than those in the SBRT plan (all P < 0.01), except for the D1000cm3 and D1500cm3 for the lung (P > 0.05). Conclusion Template-assisted 192Ir source hypofractionated SABT ensures high dose in the gross tumor volume and reduces the dose in organs at risk in the treatment of peripheral lung cancer.
ISSN:1000-8578