A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration
Background:. Allograft adipose matrix (AAM) offers a novel, off-the-shelf, and readily available natural option in the treatment of facial soft tissue volume and reconstructive deficits. AAM is a natural soft tissue supplement or replacement that can support cushioning and volume correction. A prosp...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer
2024-01-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005523 |
| _version_ | 1797341079465361408 |
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| author | Michael H. Gold, MD, FAAD Steven Fagien, MD, FACS Rod J. Rohrich, MD, FACS |
| author_facet | Michael H. Gold, MD, FAAD Steven Fagien, MD, FACS Rod J. Rohrich, MD, FACS |
| author_sort | Michael H. Gold, MD, FAAD |
| collection | DOAJ |
| description | Background:. Allograft adipose matrix (AAM) offers a novel, off-the-shelf, and readily available natural option in the treatment of facial soft tissue volume and reconstructive deficits. AAM is a natural soft tissue supplement or replacement that can support cushioning and volume correction. A prospective multicenter pilot study evaluated AAM in facial volume restoration.
Methods:. Eleven women (mean age of 55.8 ± 10.9 y) with midface volume deficit were followed up for 24 weeks after AAM treatment in this institutional review board–approved multicenter pilot study. The clinical safety and efficacy of the AAM treatment were evaluated using clinical scales and three-dimensional quantitative facial photography.
Results:. AAM was safe to address facial volume deficits, with minor site-related adverse events and discomfort that resolved within 2–4 weeks. Observations also revealed facial volume improvements throughout the study with 91% positive responders. At week 24, the subject facial satisfaction scores revealed an 86% increase compared to baseline, along with a statistically significantly improved midface fullness compared to baseline.
Conclusion:. AAM offers a natural and safe option for midface volume restoration and supports overall satisfaction and volume improvements. |
| first_indexed | 2024-03-08T10:12:39Z |
| format | Article |
| id | doaj.art-66bebd510b5a47afb5f1193e21638687 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-03-08T10:12:39Z |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-66bebd510b5a47afb5f1193e216386872024-01-29T07:01:16ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742024-01-01121e552310.1097/GOX.0000000000005523202401000-00050A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume RestorationMichael H. Gold, MD, FAAD0Steven Fagien, MD, FACS1Rod J. Rohrich, MD, FACS2From the * Gold Skin Care Center, Nashville, Tenn.‡ Aesthetic Eyelid Plastic Surgery, Boca Raton, Fla.§ Dallas Plastic Surgery Institute, Dallas, Tex.Background:. Allograft adipose matrix (AAM) offers a novel, off-the-shelf, and readily available natural option in the treatment of facial soft tissue volume and reconstructive deficits. AAM is a natural soft tissue supplement or replacement that can support cushioning and volume correction. A prospective multicenter pilot study evaluated AAM in facial volume restoration. Methods:. Eleven women (mean age of 55.8 ± 10.9 y) with midface volume deficit were followed up for 24 weeks after AAM treatment in this institutional review board–approved multicenter pilot study. The clinical safety and efficacy of the AAM treatment were evaluated using clinical scales and three-dimensional quantitative facial photography. Results:. AAM was safe to address facial volume deficits, with minor site-related adverse events and discomfort that resolved within 2–4 weeks. Observations also revealed facial volume improvements throughout the study with 91% positive responders. At week 24, the subject facial satisfaction scores revealed an 86% increase compared to baseline, along with a statistically significantly improved midface fullness compared to baseline. Conclusion:. AAM offers a natural and safe option for midface volume restoration and supports overall satisfaction and volume improvements.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005523 |
| spellingShingle | Michael H. Gold, MD, FAAD Steven Fagien, MD, FACS Rod J. Rohrich, MD, FACS A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration Plastic and Reconstructive Surgery, Global Open |
| title | A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration |
| title_full | A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration |
| title_fullStr | A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration |
| title_full_unstemmed | A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration |
| title_short | A Multicenter Pilot Study of a Novel Allograft Adipose Matrix in Malar and Prejowl Volume Restoration |
| title_sort | multicenter pilot study of a novel allograft adipose matrix in malar and prejowl volume restoration |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005523 |
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